Position title: Research Officer, Computational Systems Biology

Employer: Children’s Medical Research Institute (CMRI)

Closing date: 7th August 2020

Brief position description: The opportunity

The Computational Systems Biology (CSB) lab at CMRI is welcoming applications for a Research Officer to conduct research in the broad area of systems stem cell biology and single-cell multi-omics. The CSB lab collaborates closely with other groups and units at CMRI (e.g. Embryology) and also bioinformaticians from the School of Mathematics and Statistics, and systems biologists from Charles Perkins Centre (CPC), at the University of Sydney.

This is a three-year fixed term position with possibility for extension tenure subject to satisfactory performance, and the requirements of research projects in the Research Unit.

About the role

This position will help you building a collaboration network across multiple institutes and a track record that enables you to apply for collaborative research funding and independent research fellowship. Specific roles include (but not limited to) the following:

Lead and carry out research projects in the broad area of systems biology, stem cells biology, and single-cell multi-omics.
Prepare and publish work on scientific journals and present scientific results in national/international conferences.
Develop and co-supervise research projects for undergraduate and graduate research students.
Assist in the recruitment of research students and continuously working towards attracting new funding.
Build collaboration with different labs in CMRI and across multiple institutes/universities at Sydney (e.g. CPC and School of Mathematics and Statistics) and beyond.
About you

We are look for someone with the follow characteristics and research experience.

A PhD in an appropriate area such as (but not limited to) computational and systems biology, bioinformatics, computer science, statistics or another closely related scientific discipline.
Proven research ability, and evidence of self-motivation and research potential
Demonstrated experience with omics, bioinformatics, systems biology and molecular biology
Demonstrated experience with machine learning, deep learning and data analytics
Proven excellence in written and oral communications, interacting with a variety of researchers and stakeholders
Proven commitment to producing high quality work and a demonstrated track record of high-quality publications
Demonstrated excellence in research within bioinformatics or computational systems biology through published research in refereed journals
Proven ability to write and contribute to bioinformatic, computational, statistical, or mathematical research papers
Knowledge of stem cells and development
Computational Systems Biology group

CSB lab (https://pyanglab.github.io) combines computational ('dry') and experimental (‘wet’) expertise to understand stem cell systems. The lab resides in CMRI, Westmead, while also holding office space at both School of Mathematics and Statistics and Charles Perkins Centre, USyd, which enable ample collaboration with statisticians and bioinformaticians; computational and systems biologists; and molecular and developmental biologists.

Current focus of the lab is on transcriptional regulation in stem cells (Yang et al. Molecular Cell, 2017; Kim…Yang, Nucleic Acid Research, 2020); bulk and single-cell multi-omics analysis (Yang et al, Cell Systems, 2019; Kim…Yang, Bioinformatics, 2020); and machine learning application in systems biology (Cao…Yang, Nature Machine Intelligence, 2020). The overarching goal of the lab is to develop computational methods for characterising stem cell systems and harnessing them for tissue regeneration.

Job website: http://www.seek.com.au/job/50204904

Contact name: Pengyi Yang

Contact email: pengyi.yang@sydney.edu.au