Employer: Peter MacCallum Cancer Centre

Closing date: 13th November 2023

Brief position description: The Trigos lab focuses on understanding how different -omics layers in tumour cells and the microenvironment adapt and co-evolve as an ecosystem to drive cancer progression, resistance and metastasis with the goal of identifying novel biomarkers and targets for treatment. We address these questions using a computational top-down approach to profile patient samples collected from biospecimen collection programs and clinical trials. Throughout our projects we use a combination of bulk, single-cell and spatial -omics data, including genome sequencing, gene expression, methylation, chromatin accessibility, ctDNA, single-cell RNAseq and multiome, as well as spatial transcriptomics and proteomics platforms (e.g. Visium, OPAL, MIBI, CODEX, Nanostring Digital Spatial Profiling). 

We are based in the Computational Biology Program, which is an active community with scientists from a range of disciplines including biology, biomedicine, computer science,mathematics, statistics, as well as software engineering. We collaborate widely with scientists and clinicians in prostate cancer and multiple myeloma, including the Prostate Theranostics Imaging Centre of Excellence (ProsTIC) and the Barrie Dalgleish Centre for Myeloma and Related Blood Cancers.

We are seeking a talented, highly motivated and self-directed Postdoctoral Researcher in Computational Biology with a PhD graduate degree in Bioinformatics, Computational Biology, Genomics, Image Analysis or related. The Postdoctoral Research will lead projects understanding spatial cell-cell interactions from spatial transcriptomics and proteomics data, including the integration with other data modalities. The Postdoctoral Researcher will have the opportunity to develop projects together with the lab head, design and carry out analyses and method development (as required) with unique -omics datasets to address key translational questions. Postdocs will receive mentorship in structuring research manuscripts, writing grant applications, and developing collaborations.

For the full position description, please visit: https://careers.petermac.org/job/MELBOURNE-Postdoctoral-Fellow-Computational-Biology-VIC-3000/945024010/

Contact name: Anna Trigos

Contact email: anna.trigos@petermac.org