Bioinformatician - Cancer Research @ VIC

Employer: Peter MacCallum Cancer Centre

Closing date: 12th December 2023

Brief position description: The primary responsibility of this role is to support the bioinformatics analysis of projects within the Cancer Genomics Translational Research Centre (TRC).

The Cancer Genomics TRC is focused on supporting a range of academic and commercial translational research projects. The team provides a range of services, covering sample handling, wet-lab processing, and bioinformatics analysis.

This position is predominately focused on supporting a project involving the analysis of DNA methylation and targeted sequencing data, via the application of established bioinformatics workflows. With additional opportunities to assist with development of new workflows/tools and other analysis of other next generation sequencing data.

We are seeking a motivated bioinformatician/computational biologist with experience in analysis of next generation sequencing data, competency in R/Python and shell script programming languages. The individual will be working closely with other bioinformaticians, cancer biologist and clinicians, to deliver on translational research projects.

Job website: https://careers.petermac.org/job/MELBOURNE-Bioinformatician-Cancer-Research-VIC-3000/946272310/

Contact name: Stephen Wong

Contact email: stephen.wong@petermac.org

Research assistant/Post doc @ VIC

Employer: Florey Institute of Neurosicence and Mental Health

Closing date: 20/12/2023

Brief position description: About Us

The Florey Institute of Neuroscience and Mental Health is a medical research institute specialising in the brain and mind and is one of the world’s top 10 brain research centres. We employ exceptionally talented people who work to solve the greatest brain and mind challenges of our era. Our staff and students are the bedrock of our research and success, and we strive for excellence by fostering partnerships and empowering people. At the Florey our mission-driven culture enables our people to collaborate, thrive, learn, make ground-breaking discoveries and advance humanity through brain and mind science.

About the role:

The candidate will be responsible for:

Reporting to the chief investigator, Drs Nicholas Pan and Liang Jin with multiple tasks (with a focus on data analysis), working both as part of a team and independently.
Provide trainings to honours and HDR students within the group
Contribute to project reports, and to grant proposals and publications as appropriate
Draft and contribute to scientific materials, including literature reviews, ethics, grant submissions, protocols, and documents
Participate in team meetings and working groups and interact with group members
Undertake general administration duties, supporting the research team
Support the collective vision and mission of the Florey through
open and collaborative communication that promotes positive and respectful relationships
fostering and supporting innovation within the team and broader Institute teams
excellence in practice driven by a focus on equity, diversity and inclusivity

The successful candidate will have:

A Masters* or PhD degree in a relevant area or related discipline
Communicate highly effectively in oral and written form
Excellent and succinct writing skills
Excellent attention to detail and accuracy
Competence in use of software products for bioinformatic analysis
Relevant working experience, evidenced by e.g. publications
Experience with the below is desirable, but not essential:

Academic background in neuroscience, immunology
Experience in proteomics, scRNA sequencing
Experience in machine learning
Experience in teaching/student supervision

Job website: http://floreyinstitute.applynow.net.au/jobs/FLOREY182-research-assistant-bioinformatics-neuroscience-focused

Contact name: Nicholas Pan

Contact email: yijun.pan@unimelb.edu.au

Bioinformatics Research Officer or Research Assistant—Parental Leave Replacement @ VIC

Employer: WEHI

Closing date: 10 December 2023

Brief position description: We are seeking a talented and motivated Research Officer or Research Assistant to join the Bioinformatics Support Facility at the Walter and Eliza Hall Institute of Medical Research (WEHI) to fill a vacancy due to parental leave. While this is a short-term position, there is potential for the role to become on-going. The Support Facility forms part of WEHI’s Bioinformatics Division, one of the largest bioinformatics research groups in Australia that has achieved a reputation for developing statistical and computational methodology that is applied worldwide. The purpose of the Support Facility is to build and maintain a world-class core bioinformatics facility. It provides bioinformatic and statistical support to WEHI’s biological research groups, in addition to advancing research within the Institute.

Job website: https://wehi.wd3.myworkdayjobs.com/en-US/WEHI/job/Parkville-Victoria-Australia/Bioinformatics-Research-Officer-or-Research-Assistant-Parental-Leave-Replacement_JR2328-1

Contact name: Alexandra Garnham

Contact email: garnham.a@wehi.edu.au

Casual Biostatistician/Statistical Bioinformatician

Employer: WEHI

Closing date: 7 December 2023

Brief position description: The appointee will analyse a distinctive proteomics dataset, sourced from samples taken up to 10 years before disease onset, offering a rare chance to identify predictive disease markers. Collaborating with the Bioinformatics Division and the Centre for Healthy Ageing and Care (CFHAC), the role involves crafting and applying advanced statistical methods for large-scale proteomic datasets linked to healthy ageing and disease. The appointee will develop statistical workflows compatible with the latest proteomics data, ensuring findings are integrated into clinical diagnostics through partnerships with CFHAC's clinical associates.

Job website: https://wehi.wd3.myworkdayjobs.com/en-US/WEHI/job/Parkville-Victoria-Australia/Casual-Biostatistician-Statistical-Bioinformatician_JR2296-1

Contact name: Belinda Phipson

Contact email: phipson.b@wehi.edu.au

Computational RNA Biology Programmer @ Canberra

Employer: The Australian National University

Closing date: 29th November 2023

Brief position description: The John Curtin School of Medical Research (JCSMR) is a leading centre of biomedical research in Australia with research programs addressing fundamental problems of significance to human disease. Within this environment, The Centre for Computational Biomedical Sciences (CCBS) develops advanced computational and medical technologies to enable discovery, interpretation, and prediction in biomedical research. CCBS works in conjunction with The Shine-Dalgarno Centre for RNA Innovation (SDCRI), which aspires to drive impactful discoveries and innovations in RNA science to harness the next generation of RNA-based therapeutics and diagnostics, train and foster the future RNA research workforce, and mobilise this workforce and RNA discoveries to areas of strategic health and economic importance to the region and nation.


The Computational RNA Biology Programmer is expected to undertake work within the CCBS in the context of its activities and collaborations with the SDCRI; and will contribute to the development, application, and evaluation of machine learning methods to improve RNA molecule and delivery vector design.


For further information about this position please contact Professor Eduardo Eyras, Head, Centre for Computational Biomedical Sciences at John Curtin School of Medical Research – E: eduardo.eyras@anu.edu.au

Job website: http://jobs.anu.edu.au/jobs/programmer-computational-rna-biology-canberra-act-act-australia

Contact name: Eduardo Eyras

Contact email: eduardo.eyras@anu.edu.au

Bioinformatician - Cancer Research @ VIC

Employer: Peter MacCallum Cancer Centre

Closing date: 20th November 2023

Brief position description: This position will join the Bioinformatics Core Facility to provide bioinformatics support to next-generation sequencing and other high-throughput genomics data using best-practice methods. This position is a full time one-year, fixed term position with a prospect for a permanent position. Candidates interested in a part-time position are also encouraged to apply and put the relevant information in the cover letter.

The Bioinformatics Core Facility aims to provide all levels of bioinformatics support to research laboratories within Peter Mac. The team of bioinformaticians and engineers at the Core work alongside laboratory and clinical researchers and contribute to their experimental design, grant applications and the analysis and publication of genomic and transcriptomic data. The Core also develops and maintains software infrastructure required for bioinformatics processing, including analysis pipelines, machine learning workflows, and cloud provision systems.

This position will primarily support the bioinformatics analysis of cancer research projects by developing and maintaining analysis pipelines to be used by Peter Mac Research. This position will work and communicate closely with cell biologists, bioinformaticians, software engineers and system admins to address the analytical challenges posed by evolving genomic technologies.

Job website: https://careers.petermac.org/job/MELBOURNE-Bioinformatician-Cancer-Research-VIC-3000/936068810/

Contact name: Richard Lupat

Contact email: richard.lupat@petermac.org

Data and Research Computing Specialist @ SA

Employer: South Australian immunoGENomics Cancer Institute (SAiGENCI) at The University of Adelaide

Closing date: 30th November 2023

Brief position description: Together with the University of Adelaide’s ITDS and Research Computing teams, the South Australian immunoGENomics Cancer Institute (SAiGENCI) is inviting applications to apply for the Data and Research Computing Specialist position. This position will report to the Director, Research Infrastructure and Platforms in the Division of Research and Innovation at The University of Adelaide with an aligned responsibility to the Head, Data Sciences Unit, at The South Australian ImmunoGenomics Cancer Institute (SAiGENCI). 

The South Australian ImmunoGenomics Cancer Institute (SAiGENCI) is located in the AHMS building in Adelaide’s biomedical precinct on North Terrace. SAiGENCI undertakes world class cancer research in cancer biology, computational biology, epigenetics, and immuno-oncology. The Data and Research Computing Specialist will play a key role supporting scientists across the institute to do world-leading research.

Advances in data generation and computational analysis have increased the demand for specialist data management skills and research computing expertise. The reduction in costs of sequencing and the advancement of spatial maps, have led to the increased requirement for specialist data handling and management of big data. Large and complex data sets associated with imaging techniques, such as CosMx and single cell spatial maps, as well as genomic platforms, such as whole genome/exome sequencing and genotype arrays require storage, access, processing and analytical management. 

This role will work broadly with scientists across SAiGENCI to provide support, training and advice that will enable them to make the most of high performance computing resources and data storage options for different types of ‘omics data and imaging data. In addition, they will work closely with the University of Adelaide’s ITDS and Research Computing teams to support scientists at SAiGENCI in the management of the high performance computing requirements and the effective communication of those needs.

Essential:
- Experience in the configuration and management of research computing infrastructure, virtualised environments, etc.
- Experience in supporting the activities of an academic or research community and management of advanced research computing resources.
- Strong technical knowledge of HPC system architecture and software.
- Knowledge or demonstrated expertise in high performance computing with a diverse skill set of singularity, docker, nextflow
- Demonstrated highly developed written and oral communication skills, including ability to liaise and negotiate effectively with a wide and diverse range of people, good report writing skills.
- Understanding of the research computing needs of researchers in medical research including bioinformatics, genomics, biostatistics

Desirable:
- Knowledge of large-scale biological data and methods of data management.
- Demonstrated expertise and fundamental knowledge in biomedical research data management with current technologies including privacy compliance, data repositories, standards in metadata, research methods and research data curation and how data supports high quality research.

Qualification/s:
- Postgraduate qualifications or progress towards postgraduate qualifications and extensive relevant experience (preferably in information management, information technology, computing or data-intensive research discipline); or
- An equivalent combination of relevant experience and/or education/training (in data management or imaging processing)..

Job website: http://careers.adelaide.edu.au/cw/en/job/512920/data-and-research-computing-specialist

Contact name: Belinda Cornes

Contact email: belinda.cornes@adelaide.edu.au

Postdoctoral Fellow - Computational Biology @ VIC

Employer: Peter MacCallum Cancer Centre

Closing date: 13th November 2023

Brief position description: The Trigos lab focuses on understanding how different -omics layers in tumour cells and the microenvironment adapt and co-evolve as an ecosystem to drive cancer progression, resistance and metastasis with the goal of identifying novel biomarkers and targets for treatment. We address these questions using a computational top-down approach to profile patient samples collected from biospecimen collection programs and clinical trials. Throughout our projects we use a combination of bulk, single-cell and spatial -omics data, including genome sequencing, gene expression, methylation, chromatin accessibility, ctDNA, single-cell RNAseq and multiome, as well as spatial transcriptomics and proteomics platforms (e.g. Visium, OPAL, MIBI, CODEX, Nanostring Digital Spatial Profiling). 

We are based in the Computational Biology Program, which is an active community with scientists from a range of disciplines including biology, biomedicine, computer science,mathematics, statistics, as well as software engineering. We collaborate widely with scientists and clinicians in prostate cancer and multiple myeloma, including the Prostate Theranostics Imaging Centre of Excellence (ProsTIC) and the Barrie Dalgleish Centre for Myeloma and Related Blood Cancers.

We are seeking a talented, highly motivated and self-directed Postdoctoral Researcher in Computational Biology with a PhD graduate degree in Bioinformatics, Computational Biology, Genomics, Image Analysis or related. The Postdoctoral Research will lead projects understanding spatial cell-cell interactions from spatial transcriptomics and proteomics data, including the integration with other data modalities. The Postdoctoral Researcher will have the opportunity to develop projects together with the lab head, design and carry out analyses and method development (as required) with unique -omics datasets to address key translational questions. Postdocs will receive mentorship in structuring research manuscripts, writing grant applications, and developing collaborations.

For the full position description, please visit: https://careers.petermac.org/job/MELBOURNE-Postdoctoral-Fellow-Computational-Biology-VIC-3000/945024010/

Contact name: Anna Trigos

Contact email: anna.trigos@petermac.org

Software Engineer - Vaccine Design

Employer: CSIRO

Closing date: 29 October 2023, 11:00 pm AEDT

Brief position description: 

Acknowledgement of Country
CSIRO acknowledges the Traditional Owners of the land, sea and waters, of the area that we live and work on across Australia. We acknowledge their continuing connection to their culture and pay our respects to their Elders past and present. View our vision towards reconciliation

Child Safety
CSIRO is committed to the safety and wellbeing of all children and young people involved in our activities and programs. View our Child Safe Policy.

The Opportunity
Certified Amazon Web Services, Microsoft Azure and/or Google Cloud Platform user
Evidence of data analytics and programming – Python, Java, C++, Scala, BASH, R, Julia
Join CSIRO's AEHRC! A truly collaborative, flexible and inclusive workplace

The Australian e-health research centre (AEHRC) is CSIRO’s digital health research unit delivering innovation to the health system. It is the largest eHealth research group in Australia with more than 100 research scientists working with clinicians and industry to identify the clinical and/or health challenges. AEHRC is worldwide unique in covering the full value chain from basic science through to clinical application and assessing their impacts on Australian and international health systems.

As the Software Engineer Vaccine Design, you’ll join the Transformational Bioinformatics Group within AEHRC to develop novel bioinformatics solutions for research and industry using the latest technologies in cloud infrastructure and will be working closely with the external collaborators and stakeholders to design & architect modular bioinformatics design pipelines and standardised workflows, deployed on cloud computational and storage infrastructure.

You’ll be instrumental in bridging the gap between various bioinformatic pipelines and building a digital platform for designing RNA therapeutics, including vaccines, using cloud infrastructure, leading to the curated workflows which will enable rational modular designing and successive functional improvement of single or multi-component mRNA vaccine or therapeutic candidates. If you are fascinated in this area of research and contribute to novel bioinformatic solution, then do not hesitate to apply.

Your duties will include:
In collaboration with scientists, designing and implementing innovative cloud architecture to carry out impactful research and cater for the challenges in the health and life science domain (fast turn-around-time and large volumes of data).
Implementing ML solutions to biological research questions; Exploring novel ML methodological approaches to research questions.
Be knowledgeable about cloud services across multiple vendors (specifically AWS, Azure, GCP). 
Preparing appropriate documentation through repositories (e.g. bitbucket), project boards (e.g. trello), online communities (e.g. gist) and contributing to reports, scientific papers and blog posts.
Communicating openly, effectively and respectfully with all staff, clients and suppliers in the interests of good business practice, collaboration and enhancement of CSIRO’s reputation and a few other duties appropriate to the role.

Location: Open to any of these locations - Adelaide, SA; Canberra, ACT; Melbourne, VIC; Brisbane, QLD; Sydney, NSW

Salary: AU$105k – AU$114k plus up to 15.4% superannuation

Tenure: Specified term of up to 2 years

Reference: 93397

To be considered you will need:
A bachelor or master degree or equivalent relevant work experience in a relevant discipline area, such as Information Technology, Bioinformatics, Electrical Engineering, or Data Science.
Proven impact from developing solutions on public cloud infrastructure (AWS, Azure, GCP, Alibaba cloud) or advanced high-performance computing (HPC) with demonstrated software engineering practices (use of repositories, deployment standards, efficiency analysis).
Evidence of advanced data analytics and programming capabilities in more than one language relevant to bioinformatics (e.g. Python, Java, C++, Scala, BASH, R, Julia).
High-level written and oral communication skills with the ability to represent the research team effectively internally and externally, including the presentation of research outcomes at national and international conferences.
A sound history of publication in peer-reviewed journals and/or authorship of scientific papers, reports, grant applications or patents.
A record of scientific innovation and creativity, including the ability & willingness to incorporate novel ideas and approaches into scientific investigations.


For full details about this role please review the Position Description

Eligibility
Applications for this position are open to Australian/ New Zealand citizens and Australian permanent residents currently residing in Australia.
Appointment to this role is subject to the provision of a national police check and may be subject to other security/medical/character requirements.

Flexible Working Arrangements
We work flexibly at CSIRO, offering a range of options for how, when and where you work. 

Diversity and Inclusion
We are working hard to recruit people representing the diversity across our society, and ensure that all our people feel supported to do their best work and feel empowered to let their ideas flourish. 

About CSIRO
At CSIRO Australia's national science agency, we solve the greatest challenges through innovative science and technology. We put the safety and wellbeing of our people above all else and earn trust everywhere because we only deal in facts. We collaborate widely and generously and deliver solutions with real impact. 

CSIRO is committed to values-based leadership to inspire performance and unlock the potential of our people.

CSIRO is committed to the safety and wellbeing of all children and young people involved in our activities and programs, whether we are undertaking research, engaging with the public or nurturing future scientists in person or online. Source – CSIRO Child Safe policy 2023

Join us and start creating tomorrow today!

How to Apply
Please apply on-line and provide a cover letter and CV that best demonstrate your motivation and ability to meet the requirements of this role.

Job website: http://jobs.csiro.au/job-invite/93397/

Contact name: Shree Chattopadhyay

Contact email: careers.online@csiro.au

Ataxia Postdoc (bioinformatics) @ VIC

Employer: WEHI

Closing date: 25th October

Brief position description: The Bahlo lab is a computational biology and statistical genetics group that seeks to identify and understand genetic risk factors of human diseases, with a strong focus on neurological and retinal disorders. We leverage cutting-edge computational tools to analyse massive genomic datasets from local and international human disease cohorts to identify genetic variants associated with diseases, integrating these data with multi -omics data to gain biological understanding. Our multi-disciplinary research team collectively have expertise in many aspects of human genetics research, from rare variant analysis to GWAS studies. We have well established collaborations with molecular biologists and clinicians nationally and internationally with access to outstanding genomic cohorts.

We are seeking a highly motivated and self-directed Research Officer to join our research team focused on investigating the genetic basis of ataxia disorders in an Australian adult ataxia cohort. The position is funded by a successful Genomics Mission Medical Research Future Fund grant and continues our previously highly successful work which has led to several gene discoveries and improved diagnostics for ataxia patients.

The successful candidate will be supervised by Dr Haloom Rafehi and Prof. Melanie Bahlo and will collaborate closely with a multidisciplinary team of researchers, including bioinformaticians, molecular biologists and clinicians analysing genomic and other 'omic data from ataxia patient cohorts.

Job website: http://www.seek.com.au/job/70361914

Contact name: Haloom Rafehi

Contact email: rafehi.h@wehi.edu.au