Bioinformatics Engineer: Clinical Genomics

Employer: University of Technology Sydney

Closing date: 07/02/2018

Brief position description: The successful applicant will analyse human genome datasets with a view toward deploying long read genome sequencing in the clinical genomics setting. This person will leverage their knowledge of human clinical genomics and the importance of genomic structural variation and repetitive DNA to guide the development of further sequence analysis and genome assembly algorithms for a novel long read DNA sequencing technology.

UTS position reference: IRC103739

Job website: https://recruitment.uts.edu.au/OA_HTML/OA.jsp?OAFunc=IRC_VIS_VAC_DISPLAY&p_svid=103739&p_spid=3088872

Contact name: Aaron Darling

Contact email: aaron.darling@uts.edu.au

Research Scientist in Computational & Systems Biology

Employer: CSIRO

Closing date: Sunday 11 February 2018

Brief position description: The Position
The Synthetic Biology FSP (SynBioFSP) is developing a research portfolio which will be spread across CSIRO and a wide variety of partner organisations (universities, industry, NGOs, other research organisations, etc.), both national and international. The research portfolio is dynamic and will evolve over time on the basis of strategy and performance. Research projects will sit within one or more priority Application Domains (Environment & Biocontrol, Chemicals & Fibres, Organelles & Endosymbionts) and one or more Science Domains (Integrative Biological Modelling, Engineering Novel Biological Components, Assembling Novel Biosystems, Maximising Impact). The SynBio FSP will embed a social and behavioural science agenda to address issues around social licence to operate.
In this position, you will provide systems biology and data modelling support across two research projects, one on the in-vitro resynthesis of the lichen symbiosis and the other on the design of biorthogonal redox metabolic pathways in yeast and E. coli.

Specifically you will:
- Incorporate novel approaches to scientific investigations by adapting and/or developing original concepts and ideas for new, existing and further research.
- Analyse and integrate large omics datasets, including genomics, transcriptomics, proteomics and metabolomics.
- Use omics data for metabolic and regulatory network modelling.
- Provide bioinformatics support.

Location: Black Mountain, ACT, Australia
Salary: AU $95k - AU $103k plus up to 15.4% superannuation
Tenure: Specified term of 3 years
Reference: 53111

Job website: http://jobs.csiro.au/job/Canberra%2C-ACT-Research-Scientist-in-Computational-&-Systems-Biology/451287000/

Contact name: Cecile Gueidan

Contact email: Cecile.Gueidan@csiro.au

Bioinformatics /Computational Biology Research Assistant

Employer: CIIID Hudson Institute for Medical Research

Brief position description: The opportunity exists to join the Centre for Innate Immunity and Infectious Diseases (CIIID) as a Computational Biology Research Assistant. 

The opportunity exists to join the Centre for Innate Immunity and Infectious Diseases (CIIID) as a Computational Biology Research Assistant. This role will focus on implementing and maintaining best practice computational pipelines and data management systems for analysis of genomic and transcriptomic high throughput sequencing data, microarray datasets and bespoke datasets. The successful candidate will also assist in design and analysis of sequencing projects as a key component of the scientific program within the CiiiD.

 

Essential Skills

·       An Honours, Masters or relevant work experience in Bioinformatics, Computational Biology or Computer Science

·       Demonstrated skills in Python and R programming

·       Expertise in Linux/Unix operating systems

·       Proven ability to work independently and manage multiple projects simultaneously

·       Excellent verbal and written communication skills

·       Strong attention to detail

 

Ideal Skills

·       Demonstrated expertise in the analysis of next generation sequencing or microarray datasets

·       Experience in the analysis and interpretation of large datasets and delivering complex projects to completion.

·       Skills in the use of relational databases (e.g. MySQL)

·       Experience in cloud computing environments

·       Detailed knowledge of biologically relevant statistics and/or machine learning

·       Demonstrated experience in software development, documentation and code management

·       Experience in web design

·       Knowledge of genetics/molecular biology/biology would be an advantage but not essential

 

Data will be generated from a broad range of biological and disease contexts. Data will usually concern the innate immune response as well as on the bacterial content of the microbiome, their changes and consequences in infection, inflammation and cancer. Some aspects of these projects will involve correlation with phenotype information from animal model systems and clinical data from human studies.

 

As is standard practice, the position will be initially for 1 year, then renewable, subject to performance.  A generous remuneration package is available at a level subject to qualifications and experience.

 

The successful applicant would interact with other bioinformaticians in CiiiD, molecular biologists and with Monash e-Research to ensure the necessary compute capacity and tools were available in a standardised analysis environment and manage data storage and backup, establishment and curation of databases. The person would also be responsible for implementing, benchmarking/updating and automated running of standard QC and mapping pipelines for small and large RNA-seq, whole genome and metagenome analyses.

Contact name: Paul Hertzog, Sam Forster, Jamie Gearing

Contact email: paul.hertzog@hudson.org.au

or                      sam.forster@hudson.org.au

or                      Jamie.gearing@hudson.org.au

Postdoctoral Researcher working on single cell analysis of tumour samples

Employer: Telethon Kids Institute

Closing date: 22nd January 2018

Brief position description: Multiple postdoctoral researcher positions in Cancer Single Cell Biology: Australia

The Cancer Research Trust (http://cancerresearchtrust.org.au) has recently funded a 9 year program to enable single cell approaches to study tumour biology. The program led by Professor Alistair Forrest at the Harry Perkins Institute of Medical research is based in Perth Western Australia and is a collaboration involving all of the major hospitals, medical research institutes and Universities in the region.

Position 4 (Bioinformatics): At the Telethon Kids Institute (TKI)
Seeking to employ a postdoctoral researcher with a PhD at the time of appointment (or equivalent experience) in bioinformatics, computer science, biostatistics, molecular biology or a related discipline with an emphasis in the specific fields of computational biology, genomics and transcriptomics. The candidate will work on single cell data coming from the project under the guidance of A/Prof Timo Lassmann at the TKI.

Essential selection criteria:
• Demonstrated capacity to analyse NGS data, form hypotheses, test them and follow through to publications.
• Experience in documenting, testing and reusing code.
• Proficiency with R or other languages.
• Experience in cancer biology and analysis of single cell data is a bonus.

Link to apply and detailed criteria: 
http://bit.ly/2ywrena 
Any questions, please email Timo Lassmann Timo.Lassmann@telethonkids.org.au

Job website: http://bit.ly/2ywrena

Contact name: ALISTAIR FORREST

Contact email: alistair.forrest@perkins.uwa.edu.au

Postdoctoral Researcher working on single cell analysis of tumour samples

Employer: University of Western Australia

Closing date: 22nd January 2018

Brief position description: Multiple postdoctoral researcher positions in Cancer Single Cell Biology: Australia

The Cancer Research Trust (http://cancerresearchtrust.org.au) has recently funded a 9 year program to enable single cell approaches to study tumour biology. The program led by Professor Alistair Forrest at the Harry Perkins Institute of Medical research is based in Perth Western Australia and is a collaboration involving all of the major hospitals, medical research institutes and Universities in the region.

Position 2 (Bioinformatics): At the Harry Perkins Institute of Medical Research
Seeking to employ a postdoctoral researcher with a PhD at the time of appointment (or equivalent experience) in bioinformatics, computer science, biostatistics, molecular biology or a related discipline with an emphasis in the specific fields of bioinformatics, genomics and systems biology. The candidate will be working directly with Prof Forrest and his team on cancer-stroma cell-to-cell communication networks and on heterogeneity of drug target expression.

Essential selection criteria:
• Demonstrated capacity to analyse NGS data, form hypotheses, test them and follow through to publications.
• Experience in documenting, testing and reusing code.
• Proficiency with R or other languages.
• Experience in cancer biology and analysis of single cell data is a bonus.

Link to apply and detailed criteria: 
http://bit.ly/2AzEvRO 
Any questions, please email

Job website: http://bit.ly/2AzEvRO

Contact name: ALISTAIR FORREST

Contact email: alistair.forrest@perkins.uwa.edu.au

Bioinformatics Analyst, Sydney

Employer: Victor Chang Cardiac Research Institute

Closing date: 31/12/2017

Brief position description: We are seeking a bioinformatics analyst to join the Computational Genomics Laboratory, led by Dr Eleni Giannoulatou. The successful candidate will be involved in the analysis of large next-generation sequencing datasets and the development of quantitative approaches to identify the genetic causes of cardiovascular diseases with a particular focus on Congenital Heart Disease. The ideal candidate will have:
• Bachelor’s degree in bioinformatics, computer science, statistics, science, engineering or a relevant quantitative field
• Experience with a statistical programming language (R/Bioconductor or Matlab) and a scripting language (Perl or Python) 
• Excellent computational and mathematical skills
• Background knowledge in biology and interest in genetics
• Demonstrated capacity to work as a team member and independently
• Excellent interpersonal and communication skills
Please address the selection criteria in a cover letter.

Job website: https://www.victorchang.edu.au/uploads/Advertisement-RA-Giannoulatou-Lab-Nov-2017.pdf

Contact name: Eleni Giannoulatou

Contact email: e.giannoulatou@victorchang.edu.au

Postdoctoral Scientist in Computational Genomics, Sydney

Employer: Victor Chang Cardiac Research Institute

Closing date: 31/12/2017

Brief position description: We are seeking an enthusiastic post-doctoral scientist to join the Computational Genomics Laboratory, led by Dr Eleni Giannoulatou. The successful candidate will be involved in the analysis of large next-generation sequencing datasets and the development of quantitative approaches to identify the genetic causes of cardiovascular diseases with a particular focus on Congenital Heart Disease. The ideal candidate will have:
• PhD in computational biology, bioinformatics, statistical genetics, or a relevant quantitative field with a demonstrated aptitude for bioinformatics research
• Experience with a statistical programming language (R/Bioconductor or Matlab) and a scripting language (Perl or Python) 
• Excellent computational and mathematical skills
• Strong up-to-date background in bioinformatics and its applications to genetics and next-generation sequencing
• Demonstrated capacity to work as a team member and independently and potential to supervise students
• Excellent interpersonal and communication skills
Please address the selection criteria in a cover letter.

Job website: https://www.victorchang.edu.au/uploads/Advertisement-PDS-Giannoulatou-Lab-Nov-2017.pdf

Contact name: Eleni Giannoulatou

Contact email: e.giannoulatou@victorchang.edu.au

Postdoctoral Researcher - Bioinformatics, Cairns

Employer: James Cook University

Closing date: January 7th, 2018

Brief position description: Provide expert advice and data analysis across a wide range of strategic multidisciplinary research projects in the field of tropical health and medicine.

We offer an exciting opportunity for a Research Fellow, Bioinformatics to join our world-leading institution at James Cook University (JCU). A fixed term appointment, this position is based in Cairns in picturesque Tropical North Queensland, where you can enjoy a tropical lifestyle whilst still achieving your career goals. 

Providing expert advice and data analysis across a wide range of strategic multidisciplinary research projects, you will have the opportunity to focus on a variety of topics including infectious disease genomics, microbiome analysis, biological determinants of chronic disease, and personalised medicine within Northern Queensland hospitals. You will also be expected to conduct internationally recognised research in biomedical sciences using bioinformatics methods.

Job website: http://www.jcu.edu.au/careers-at-jcu/vacancies/research-jobs

Contact name: Matt Field

Contact email: matt.field@jcu.edu.au

Postdoctoral Researcher Systems Biology/Personalized Medicine, Perth, Australia

Employer: Telethon Kids Institute

Closing date: 31 Dec 2017

Brief position description: The laboratories of Dr Anthony Bosco and Dr Parwinder Kaur have a joint opening for a postdoctoral position in computational systems biology. The position is part of a larger effort to establish a competitive personalised medicine program at the Telethon Kids Institute.

The postdoc will be involved in developing and applying state of the art computational approaches for genomic data analysis, data integration, network inference, and personalised risk stratification. A strong focus of the position will be to identify the molecular states that underpin phenotypic states, and make predictions about actionable possibilities to push biological systems between opposing molecular states in a directed manner. A broad range of genomic data sets will be available for analysis, including Hi-C, whole genomic sequencing, whole exome sequencing, epigenetic profiles, transcriptomics, single cell transcriptomics, metabolomics, and microbiome data. Data will be generated from diverse experimental settings, including experimental human, mouse, and rat models, birth cohort studies, human clinical trials, and experimental perturbations. The position represents an exciting opportunity to work at the crossroads between basic science and clinical practice. The successful candidate will have the unique opportunity to be part of a multidisciplinary team comprised of biologists, molecular biologists, clinicians, statisticians, mathematicians, and computational biologists. The successful candidate should have:

A PhD in a relevant subject area (e.g Computational Biology, Computer Science, Statistics or Mathematics) and a background in programming and command line UNIX/ Linux
Experience in the analysis of next generation sequencing data
The following traits: creative, ambitious, enthusiastic, self-motivated, proactive, passionate, reliable, hard-working, good writing and communication skills.
At least one publication
Ability to work independently and as part of a team
Experience with supercomputing clusters would be advantageous

This is a Full time/Fixed term role for 1 year with the possibility of extension. Remuneration package includes access to generous salary packaging.

Job website: http://www.telethonkids.org.au/be-involved/career-opportunities/current-vacancies/postdoctoral-researcher/

Contact name: Parwinder Kaur

Contact email: parwinder.kaur@telethonkids.org.au

Genomics Informatician, Adelaide

Employer: SA Pathology

Closing date: 1 December, 2017

Brief position description: Full time, Ongoing - $83,509 - $93,437 - ASO5

Working with an enthusiastic team of clinical, scientific and technical staff in the exciting and expanding area of clinical genomics, this is a great opportunity to improve the health and wellbeing of South Australians. The incumbent will work in diagnostic and clinical translational genomics to improve diagnoses of genetic diseases including cancer. Our laboratory has strong clinical partnerships to spearhead clinical implementation of genomics and we are national leaders in the provision of targeted gene panel and whole-exome sequencing for diagnostics. 

The Genome Informatician applies technical expertise in bioinformatics and genome analysis to contribute to the delivery of high-throughput genetic testing services. The incumbent will implement and maintain genome analysis pipelines for diagnostic applications from targeted and genome-scale next-generation sequencing and show great attention to detail for ensuring the quality of analysis solutions.

The Genome Informatician will have practical experience in bioinformatics and computational pipeline design and demonstrated aptitude to implement effective bioinformatics analysis solutions. The Genome Informatician will effectively prioritize tasks to maintain productivity and participate in research activities, as appropriate.

The South Australian public sector promotes diversity and flexible ways of working including part-time. Applicants are encouraged to discuss the flexible working arrangements for this role.

Job website: http://jobs.sahealthcareers.com.au/caw/en/job/636373/genomics-informatician

Contact name: Karin Kassahn

Contact email: Karin.Kassahn@sa.gov.au