Position title: Genetic Counsellor
Employer: Garvan Institute of Medical Research
Closing date: 05-12-2019
Brief position description: The Garvan Institute of Medical Research (Garvan) is one of Australia’s leading medical research institutes, with over 600 scientists, students and support staff. Its mission is to make significant contributions to medical research that will change the directions of science and medicine and have major impacts on human health. Garvan’s research encompasses immunology, bone biology, neuroscience, diabetes and metabolism, cancer, and genomics and epigenetics. These research activities are organised within four themes: Cancer, Inflammatory Diseases, Healthy Aging, and Genomics, and two Centres: the Kinghorn Centre for Clinical Genomics and the Garvan-Weizmann Centre for Cellular Genomics.
The Kinghorn Centre for Clinical Genomics (KCCG), established by the Garvan Institute is an Australian research and sequencing centre delivering genomic information for clinical use. The KCCG facilitates genome-based research, particularly in cancer and monogenic diseases, but also in complex disease such as diabetes, osteoporosis and immunological disease. Our vision is to translate medical research into clinical care in Australia and beyond by integrating sequencing, bioinformatics and data management in a cutting-edge Genomics research environment.
The Opportunity
The genetic counsellor will contribute to the development and delivery of a range of projects in line with established objectives of the Clinical Translation Group in KCCG. Specifically, to coordinate with the establishment and evaluate a National Genomics Research Resource Centre (NGRRC) which will bring together researchers, research participants, genetic counsellors, clinicians as well as clinical genetic services to ensure nationally consistent approach to providing clinically actionable germline genomic information generated through research. Once the NGRRC is established the genetic counsellor will provide genetic counselling to research participants.
Reporting to the Head of KCCG - Scientific, this is a two year fixed term position with a potential to extend. The key responsibilities include:
- Project manage establishing the NGRRC including a web-based platform with a tailored messaging system, 1800 telephone line accessible to researchers and research participants and online resources for researchers and research participants.
- Provide genetic counselling to research participants notified of clinically actionable genetic information with on-referral to clinical genetic services.
- Prepare and maintain documentation for reporting, monitoring and evaluation purposes to ensure accessibility of quality information and contribute to the achievement of NGRRC project outcomes.
- Contribute to the evaluation of the NGRRC.
- All staff are required to comply with Garvan’s Work Health & Safety (WHS) Policy and work in accordance with the WHS management system at all times.
About You
- A postgraduate qualification in Genetic Counselling
- Human Genetics Society of Australasia (HGSA) Board eligible Associate Genetic Counsellor, or HGSA certified Genetic - Counsellor and a current financial member of the HGSA and Australasian Society of Genetic Counsellors (ASGC)
- Experience in project management desirable in a professional, clinical or research environment
- Excellent organisational and interpersonal skills with the ability to innovate and achieve results
- Clear and articulate communication skills both written and verbal with ability to work independently with multiple stakeholders
- Advanced computer skills, with fluency in a variety of software packages including Word, Excel and PowerPoint
- Experienced in the use of databases, writing and presenting documents and reports, as well as using online library searching software
How to Apply
All applications must include a cover letter, resume including at least 2 referees and copies of relevant qualifications / academic transcripts and apply in the company website.
Closing Date
The position will remain open until filled. As we will be reviewing applications as they are received, we encourage you to submit yours as soon as possible.
Job website: garvan.wd3.myworkdayjobs.com/en-US/garvan_institute/job/Sydney/Genetic-Counsellor_PRF5282-1
Contact name: Shree Chattopadhyay
Contact email: shreec@garvan.org.au
Computational Biology Postdoc @ Sydney
Employer: Garvan Institute of Medical Research
Closing date: 30-11-2019
Brief position description: The Garvan Institute of Medical Research (Garvan) is one of Australia’s leading medical research institutes, with over 600 scientists, students and support staff. Its mission is to make significant contributions to medical research that will change the directions of science and medicine and have major impacts on human health. Garvan’s research encompasses immunology, bone biology, neuroscience, diabetes and metabolism, cancer, and genomics and epigenetics. These research activities are organised within four themes: Cancer, Inflammatory Diseases, Healthy Aging, and Genomics, and two Centres: the Kinghorn Centre for Clinical Genomics and the Garvan-Weizmann Centre for Cellular Genomics.
The Kinghorn Centre for Clinical Genomics (KCCG), established by the Garvan Institute is an Australian research and sequencing centre delivering genomic information for clinical use. The KCCG facilitates genome-based research, particularly in cancer and monogenic diseases, but also in complex disease such as diabetes, osteoporosis and immunological disease. Our vision is to translate medical research into clinical care in Australia and beyond by integrating sequencing, bioinformatics and data management in a cutting-edge Genomics research environment.
The Translational Genome Informatics Group (TIG) within KCCG is a multidisciplinary team of bioinformaticians, statisticians, software engineers and clinical researchers, developing and deploying bioinformatic methods to study genomic variation, focussed on particular diseases. This work includes rare monogenic disease and cancer as well as complex diseases such as diabetes, osteoporosis and immunological immune diseases.
This position will work with the team leader of the Translational Genome Informatics Group to perform research into translational genomics, including developing, streamlining, and validating approaches for analysing and interpreting multi-omic data with the focus on clinical translation.
The role will be responsible for developing new bioinformatic approaches to study unique aspects of various diseases, and incorporate these into the analytical pipeline. These methods should be developed in a manner consistent with KCCG’s development practices, so that they can be translated into the clinical pipeline. There is scope within this position to perform genomics and bioinformatics research, publish scientific papers, and to pursue independent funding.
The Opportunity
Reporting to the Head of Translational Genomics, this position will be responsible for helping to provide direction and support in clinical genomics, genome informatics and translational research in cancer genomics. This will include:
Undertaking and directing translational research with an emphasis on developing biological insights that are relevant to patient outcomes.
Improve the breadth, quality and efficiency of existing genomic analysis pipelines, through development of improved bioinformatics approaches.
Develop approaches to optimise and streamline interpretation of genomes.
Occasionally represent KCCG at events, or talks with external stakeholders.
Staying abreast on advances in genomics and next generation sequencing technology in general as well as maintaining knowledge about clinical genomic testing and personalised medicine.
The position will be offered full-time for 2 years in the first instance.
About You
PhD degree in a related area of science, or equivalent, or Master’s degree with at least 3 years of experience
Highly developed skills in bioinformatics and genomics
Strong expertise in working with next-generation sequencing data
Ability to develop, manage and maintain internal and external relationships
Highly developed written and verbal communications skills
Project management skills
Desired
Strong expertise in clinical interpretation of genomic data
Software engineering skills: source control management, unit and regression testing, continuous integration
Expertise in developing diagnostic assays, and assessing their analytical performance
How to Apply
All applications must include a cover letter, resume including at least 2 referees and copies of relevant qualifications / academic transcripts
Closing Date
The position will remain open until filled. As we will be reviewing applications as they are received, we encourage you to submit yours as soon as possible.
Job website: http://garvan.wd3.myworkdayjobs.com/en-US/garvan_institute/job/Sydney/Senior-Computational-Biologist_PRF5142-1
Contact name: Shree Chattopadhyay
Contact email: shreec@garvan.org.au
Head - Computational Biology @ Sydney
Employer: Garvan Institute of Medical Research
Closing date: 29-11-2019
Brief position description: The Garvan Institute of Medical Research (Garvan) is one of Australia’s leading medical research institutes, with over 600 scientists, students and support staff. Its mission is to make significant contributions to medical research that will change the directions of science and medicine and have major impacts on human health. Garvan’s research encompasses immunology, bone biology, neuroscience, diabetes and metabolism, cancer, and genomics and epigenetics. These research activities are organised within four themes: Cancer, Inflammatory Diseases, Healthy Aging, and Genomics, and two Centres: the Kinghorn Centre for Clinical Genomics and the Garvan-Weizmann Centre for Cellular Genomics.
The Kinghorn Centre for Clinical Genomics (KCCG), established by the Garvan Institute is an Australian research and sequencing centre delivering genomic information for clinical use. The KCCG facilitates genome-based research, particularly in cancer and monogenic diseases, but also in complex disease such as diabetes, osteoporosis and immunological disease. Our vision is to translate medical research into clinical care in Australia and beyond by integrating sequencing, bioinformatics and data management in a cutting-edge Genomics research environment.
The Opportunity
We are now seeking a Head of Computational Biology to lead a team in advancing the state-of-the-art in multi-omics analysis. The primary specific objectives of the team are: (1) establish computational best practices for analysis of -omics datasets and bring these in-house along with key public datasets (2) development of new tools and algorithms to facilitate interpretation of multi-omics datasets and (3) collaboration with experimental research groups to efficiently analyse large datasets.
This leadership role will be responsible for coordinating and executing relevant projects and activities within the Computational Biology group. They will ensure KCCG remains at the forefront of computational approaches and place emphasis on methodologies that have transformative potential and could be used in clinical practice.
The successful candidate will demonstrate the following key skills and attributes:
A PhD in genomics or a related field
Strong background in bioinformatics, with at least 5 years of experience
Strong expertise in clinical interpretation of genomic data
Strong expertise in working with next-generation sequencing data
Experience in team building, leadership and collaboration
In return the Head of the Computational Biology group will have access to a competitive salary, participation in local and international conferences, and publishing opportunities in a rich interdisciplinary research environment.
https://www.garvan.org.au/research/kinghorn-centre-for-clinical-genomics/research-programs
Remuneration for this position is competitive and commensurate on experience with additional salary packaging benefits. The position is based at The Kinghorn Cancer Centre, a new joint initiative of the Garvan Institute of Medical Research and St. Vincent’s Hospital, located in inner-city Darlinghurst.
http://kinghorncancercentre.com. The Kinghorn is rapidly developing expertise and large capacity in cancer genomics and informatics and will provide a supportive and exciting environment for the fellow.
For further details, please contact Sarah Kummerfeld by e-mail (s.kummerfeld@garvan.org.au).
How to Apply
Your application must include:
A cover letter
Your resume including 2 referees
Copies of relevant qualifications / academic transcripts
Closing Date
The position will remain open until filled. As we will be reviewing applications as they are received, we encourage you to submit yours as soon as possible.
Job website: http://garvan.wd3.myworkdayjobs.com/en-US/garvan_institute/job/Sydney/Head---Computational-Biology_PRF5235-2
Contact name: Shree Chattopadhyay
Contact email: shreec@garvan.org.au
Bioinformatician @ Sydney
Employer: Garvan Institute of Medical Research
Closing date: 28-11-2019
Brief position description: The Garvan Institute of Medical Research (Garvan) is one of Australia’s leading medical research institutes, with over 600 scientists, students and support staff. Its mission is to make significant contributions to medical research that will change the directions of science and medicine and have major impacts on human health. Garvan’s research encompasses genomics and epigenetics, cancer, immunology, bone biology, neuroscience, and diabetes and metabolism. These research activities are organised within four themes: Genomics, Cancer, Inflammatory Diseases, and Healthy Aging, and two Centres: the Kinghorn Centre for Clinical Genomics and the Garvan-Weizmann Centre for Cellular Genomics.
The Human Comparative and Prostate Cancer Genomics (HCPCG) Laboratory is focused on understanding the complexities of the human and cancer genome and how genomic variation has shaped human diversity, health, cancer evolution, risk and outcome.
This is a newly funded position, from the Australian National Health and Medical Research Council (NHMRC), to examine genomic alterations contributing to both ethnic disparities and those driving aggressive prostate cancer. The project is prefaced on the hypothesis that somatic (acquired) genomic alterations are fundamental drivers of clinical heterogeneity and treatment response in prostate cancer. Thus, the project seeks to identify the somatic genomic landscape as potential biomarkers of disease and treatment outcome by using whole-genome sequencing of tumour and matched normal patient samples.
The Opportunity
Reporting to the Head of HCPCG, the Bioinformatics Research Officer will focus on the implementation of high-throughput computational tools to analyse next-generation sequencing (NGS) data to identify somatic variations associated with prostate cancer.
This is a one year full time opportunity in the first instance with the possibility to extend.
Key Responsibilities
Perform computational and statistical analyses of whole genome sequencing data
Implement existing bioinformatics tools necessary for large-scale population-level genome analysis
Manage movement and storage of genomic data related to the project
Ensure appropriate written documentation of work
Work independently and as part of a team
Support writing of manuscripts related to the project
Other duties relevant to the role
About You
Postgraduate Degree in a relevant field (e.g. bioinformatics, cancer genomics, or comparative genomics) or Bachelors’ Degree with demonstrated experiences in these fields
Experience with bioinformatics or computational analyses, particularly for NGS data
Familiarity of NGS technologies, particularly of the Illumina platform
Experience with installing and implementing existing bioinformatics software
Familiarity with the commandline and use of HPC resource
How to Apply
All applications must include:
A cover letter
Your resume including at least 2 referees
Copies of relevant qualifications / academic transcripts
Closing Date
The position will remain open until filled. As we will be reviewing applications as they are received, we encourage you to submit yours as soon as possible.
Job website: https://garvan.wd3.myworkdayjobs.com/en-US/garvan_institute/job/Sydney/Bioinformatician_PRF5166-2
Contact name: Shree Chattopadhyay
Contact email: shreec@garvan.org.au
Bioinformatics Research Assistant @ Melbourne
Employer: Murdoch Children's Research Institute
Closing date: 7 November 2019
Brief position description: High throughput sequencing has revolutionised both the diagnosis of genetic disorders and the discovery of novel disease associated genes. Despite this success, a substantial fraction of patients remain undiagnosed, even after undergoing clinical genomic testing. The Translational Bioinformatics Research Group uses a combination of genomic transcriptomic sequencing, advanced computational analysis and functional genomic approaches to understand the genetic causes of rare and undiagnosed disorders.
A talented Bioinformatician research assistant is now required to support the activities of this multi-disciplinary team including clinicians, bioinformaticians and wet lab researchers. The successful candidate will be responsible for developing, testing and supporting bioinformatic pipelines and end user applications, as well as performing ad hoc data and statistical analysis. The role applies a combination of software engineering and bioinformatic skills to produce high quality, tested, documented, robust and well-designed informatics solutions.
Job website: https://career10.successfactors.com/career?career%5fns=job%5flisting&company=C0007531036P&navBarLevel=JOB%5fSEARCH&rcm%5fsite%5flocale=en%5fGB&career_job_req_id=16979&selected_lang=en_GB&jobAlertController_jobAlertId=&jobAlertController_jobAlertName=&_s.crb=bXHlB7RuCvuVS%2fOnoMnN1bR7jUA%3d
Contact name: Cas Simons
Contact email: cas.simons@mcri.edu.au
Postdoc or research fellow in bioinformatics @ University of Massachusetts
Employer: University of Massachusetts Medical School
Closing date: 1/1/2020
Brief position description: We are seeking a highly motivated, creative and independent individual to join our program to create algorithms to create accurate gene and isoform annotations in a collaboration between the UMMS Bioinformatics Core (https://www.umassmed.edu/biocore) and Garber laboratory (Computational Biology, http://garberlab.umassmed.edu). We are pursuing a modeling, data centric, approach that integrates multiple RNA-Seq libraries. This is a unique opportunity for building, testing and refining computational models to create more accurate gene/isoform annotations. The person hired for this position will lead the data handling, analysis and algorithm development efforts. As such the ideal candidate will be intimately familiar with machine learning, classification and clustering algorithms, sequencing technologies and have a working knowledge of computational biology.
Responsibilities *
● Responsible for analysis of bulk RNA-Seq data ● Statistical modeling of genomics data ● Development of computational tools for de-novo transcriptome assembly using RNA-Seq data ● Develop, validate, and compare the performance of prediction models. ● Use demonstrated scientific creativity, collaboration with others, and independent thought to expand technical capabilities and identify new research opportunities
Qualifications *
● Ph.D or masters degree in Bioinformatics, Computational Biology, Physics, Computer Science, Statistics or related field
● Working knowledge of computational biology and sequencing technologies
● Fluency in at least one scripting language (e.g. Python, Perl) and good knowledge of non-scripting languages (e.g. C++)
● ANSI sql and nosql knowledge to fast and scalable databases
● Strong publication record and excellent communication skills
● Excellent organization and time management skills
● Must be able to handle a variety of tasks and to adapt to a highly dynamic environment
Job website: https://www.umassmed.edu/biocore/about-us/join-our-team/
Contact name: Alper Kucukural
Contact email: alper.kucukural@umassmed.edu
Assistant Professor in Systems Biology @ Harvard University
Employer: Harvard Medical School
Closing date: 31 October 2019
Brief position description: The Department of Systems Biology at Harvard Medical School invites applications for an Assistant Professor position. We seek researchers who define and address fundamental and/or applied problems in biology or medicine, and who use quantitative experimental, computational, synthetic and/or theoretical approaches in their work.
The Department faculty have diverse backgrounds and interests in cell biology, biochemistry, physics, mathematics, chemistry, computer science, engineering and medicine. We offer a lively, family-friendly and supportive environment in which to perform interdisciplinary science, with the benefit of significant scientific and scholarly resources. We encourage team science, entrepreneurship and innovation, including in the area of mentoring and developing the next generation of scientists with diverse backgrounds and interests. We are committed to building a diverse faculty and we strongly encourage applications from, or nominations of, female and minority candidates.
The successful candidate will become a member of Harvard University’s Ph.D. Program in Systems, Synthetic and Quantitative Biology, a cross-campus interdisciplinary program that attracts extraordinary graduate students.
The deadline for applications is October 31st, 2019. Interviews will occur in two phases, first over video conference (early December) and then in person (weeks of 10 Feb and 24 Feb 2020).
We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or any other characteristic protected by law.
For questions, please e-mail Search_SystemsBiology@hms.harvard.edu. For application instructions, and to apply, please go to https://academicpositions.harvard.edu/postings/9257
Job website: https://academicpositions.harvard.edu/postings/9257
Contact name: Angela DePace
Contact email: Search_SystemsBiology@hms.harvard.edu
Bioinformatician @ Auckland
Employer: New Zealand Ministry for Primary Industries
Closing date: 25 October 2019
Brief position description: The Ministry for Primary Industries' Plant Health & Environment Laboratory (PHEL) in Auckland has a fixed-term vacancy (36 months) for a bioinformatician to work on a project to develop a bioinformatics toolkit for the detection of known viruses and the discovery of novel viruses from high-throughput sequencing data. The toolkit will be used to support the work of both the PHEL and the Animal Health Laboratory in Wallaceville. In this role, you will be expected to develop an in-house automated bioinformatics toolkit for the screening of viruses in plant and animal samples of biosecurity importance. For the toolkit to be intuitive and user-friendly, you will be expected to develop a windows-based software with an easy-to-use graphical user interface to allow the laboratory diagnosticians to easily perform data analysis.
Job website: https://jobs.govt.nz/jobs/MPI19-1410388
Contact name: Elvis Madar
Contact email: Elvis.Madar@mpi.govt.nz
Postdoctoral Research Fellow @ Melbourne
Employer: Institute of Vector Borne Disease - Monash University
Closing date: 27 Oct
Brief position description: The Vector and Pathogen Genomics group at the Institute of Vector-Borne disease at Monash University is looking for a skilled postdoctoral Research Fellow to investigate genomic rearrangement and mobile element insertion in Aedes aegypti and its effect on gene flow in wild populations. As well as being a fascinating aspect of genome evolution, this is also a subject of prime interest to the work of the World Mosquito Program and their global network of Wolbachia-based interventions into dengue and Zika transmission.
In our group we apply omics tools to vectors, viruses and parasites in order to better understand disease transmission and develop tools for disease surveillance and control. Specific interests of the group include population structure and speciation in mosquito vectors, pathogen diversity and relatedness, pathogen-vector interactions and genomic epidemiology.
The role would suit a computational biologist looking to work in an important field of infectious disease research, or a skilled dipteran biologist who would like to pursue a postdoc in a computational field. Researchers with previous experience in statistical / population genetics or genomic evolution in insect species are encouraged to apply.
Job website: http://careers.pageuppeople.com/513/cw/en/job/594587/research-fellow
Contact name: Seth Redmond
Contact email: seth.redmond@monash.edu
Post-doctoral Research Officer / Senior Post-doctoral Research Officer @ WEHI
Employer:The Walter and Eliza Hall Institute
Closing date:31/10/2019
Brief position description:Overview
This position offers an opportunity to join the research group of Associate Professor Melissa Davis in the Bioinformatics Division at the Walter and Eliza Hall Institute on a 3 year contract at either Level A or Level B, depending on experience.
The Postdoctoral Research Officer in the Davis Laboratory will undertake research projects in computational cancer biology, including the analysis multi-omics and clinical data associated with drug treatments and response to therapies. They will be expected to undertake high quality research aligned with the interests of the laboratory, and communicate this research through presentations and the production of manuscripts. They will have the opportunity to undertake student supervision, and will participate in the preparation of funding applications related to their research.
Key responsibilities
• Analysis and integration of multi-omics data associated with responses to drugs in cell lines and other models of disease
• Identify opportunities for innovative research and develop and drive novel work aligned with the interests of the group
• Undertake collaborative research projects to study plasticity and cellular differentiation programs in breast cancer to study progression and metastasis
• Prepare reports and communicate effectively with collaborators project stakeholders
• Work effectively with other lab members on joint projects.
• Prepare manuscripts for publication in refereed journals.
• Present research findings in seminars and at national and international conferences.
• Participate in the management and supervision of RHD students
Job website:http://www.wehi.edu.au/research-officersenior-research-officer
Contact name:Melissa Davis
Contact email:davis.m@wehi.edu.au