Position title: Computational Biologist/Bioinformatician - Exceptional Responders Study
Employer: Garvan Institute of Medical Research
Closing date: 31/08/2020
Brief position description: The Garvan Institute of Medical Research brings together world-leading clinicians and basic and translational researchers to break down barriers between traditional scientific disciplines and find solutions to disease. Founded in 1963, Garvan’s mission is to harness all the information encoded in our genome to better diagnose, treat, predict and prevent disease.
Our scientists work across four intersecting research themes: medical genomics, epigenetics, and cellular genomics; diseases of immunity and inflammation; cancer; and diseases of ageing affecting bone, brain and metabolism. And three major Centres: the Kinghorn Centre for Clinical Genomics, the Garvan-Weizmann Centre for Cellular Genomics, and the Centre for Population Genomics.
The Kinghorn Centre for Clinical Genomics (KCCG's) Translational Genome Informatics Group (TIG) is a multidisciplinary team of bioinformaticians, statisticians, software engineers and clinical researchers. The team develops and applies computational methods to better understand human disease. We take a collaborative approach, working closely with experimental researchers across Garvan to tackle biological problems that address critical unmet medical needs.
The Opportunity
The Exceptional Responders Program (ExcRes) is a Nationally-recruiting initiative to progress precision cancer medicine through genomic analysis of treatment-outliers. ExcRes collaborates with cancer clinicians nationally to recruit patients who have had an unusual or unexpected response to anti-cancer treatment. This position will analyse multi-omic data from exceptional responders to tease out the molecular mechanisms driving their unusual response to therapy.
This is a one-year full-time role. We are happy to provide remote on-boarding (for intra/ interstate) employees keeping the current pandemic in mind and considering health and safety of our employees as our top priority.
Key Responsibilities
This position will be responsible for helping to provide direction and support in clinical genomics, genome informatics and translational research. This will include:
Analysing multi-omic data collected from exceptional responders
Identifying appropriate matched controls from in-house and public datasets
Working closely with the ExcRes team to interpret sequence data and design follow on studies
Developing databases for storage of cohort metadata and interfaces to provide access to researchers.
Staying abreast on advances in genomics and next generation sequencing technology in general as well as maintaining knowledge about clinical genomic testing and personalised medicine
Occasionally represent KCCG at events, or talks with external stakeholders
About You
In order to be successful in this position, you will demonstrate the following key skills and attributes:
PhD in a related area of science or equivalent or Bachelor's degree and at least 3 years of experience
Highly developed skills in bioinformatics and genomics
Ability to develop, manage and maintain internal and external relationships
Excellent problem-solving ability with good communication skills both verbal and written
Project management skills with the ability to work independently and yet amicably in a team environment to meet deadlines
Desirable
Experience working with next-generation sequencing data
Experience analysing cancer genomic data
Strong track record of peer review publication
How to Apply
Australian/NZ citizen, permanent resident or other applicants with full working rights can only apply. All applications must include a cover letter along with your resume with at least two referees. We are reviewing applications as they are received. This position will remain open until end of August 2020. You can visit external career page on Garvan website to refer to other similar roles.
Job website: http://garvan.wd3.myworkdayjobs.com/en-US/garvan_institute/job/Sydney/Computational-Biologist-Bioinformatician---Exceptional-Responders-Study_PRF5628-1
Contact name: Michelle Earle
Contact email: m.earle@garvan.org.au