Position title: Bioinformatics Research Officer - Cancer
Employer: Garvan Institute of Medical Research
Closing date: 30/09/2020
Brief position description: The Garvan Institute of Medical Research brings together world-leading clinicians and basic and translational researchers to break down barriers between traditional scientific disciplines and find solutions to disease. Founded in 1963, Garvan’s mission is to harness all the information encoded in our genome to better diagnose, treat, predict and prevent disease.
Our scientists work across four intersecting research themes: medical genomics, epigenetics, and cellular genomics; diseases of immunity and inflammation; cancer; and diseases of ageing affecting bone, brain and metabolism. In addition, three major Centres: The Kinghorn Centre for Clinical Genomics, the Garvan-Weizmann Centre for Cellular Genomics, and the Centre for Population Genomics.
The Opportunity
Reporting to A/Prof Elgene Lim and Dr Liz Caldon as a part of Connie Johnson Breast Cancer Research Group and Replication and Genome Stability Group, Cancer Research Division the Bioinformatics Research Officer is accountable under direction for conducting research that seeks to identify the biological, genetic and molecular processes in breast cancer. Specifically, this position will be responsible for leading the analysis of transcriptomics, genomic and single cell datasets.
A high level of interaction with other bioinformaticians, ROs, RAs and PhD students within the Cancer Research Division is essential.
As the project develops, additional RAs and PhD students may be recruited to the project and the Bioinformatics Research Officer would be expected to assist in their supervision. Assistance in the preparation of research grant proposals, presentations and publications will be expected.
This is a two-year full time opportunity to start.
Key Responsibilities
Recording and assisting with design and interpretation of experimental procedures and results
Conducting leading-edge informatic analysis of genetic and genomic datasets
Working collaboratively and flexibly across multiple projects that may engage different bioinformatic skill sets.
Regular meeting with A/Prof Elgene Lim and Dr Liz Caldon and members of the Cancer Research Division to discuss and review current and future techniques and experiments
Making presentations of research progress to the Cancer Research Division and other collaborative groups as required
Undertaking several research projects in an efficient and timely manner and have the outcomes of these projects published under joint authorship in leading scientific journals.
Providing general research guidance to more junior research staff whose work might have an impact on wider division research goals
About You
Possess a Masters or PhD in Bioinformatics or equivalent experience in a related field
Advanced user of the R programming language and R-based statistical packages and tools, such as those available from the Bioconductor project for high throughput genomic data analysis
The analysis of next generation sequencing data, including single cell RNA-Seq
Running informatic jobs on high performance computing systems
Data visualisation
Good knowledge of statistics and presentation of molecular/clinical data
Experience in the analysis and interpretation of large genomic data sets (WGS, RNAseq)
Excellent computational background, especially in the management of large data sets in unix/linux environment
High proficiency in programming and scripting languages (e.g. C/C++, Java, Perl, Python)
A proven track record, e.g. publications, grants, software/tool development
Familiarity with the ethical issues and guidelines relating to the use of human tissue and clinical data for research
Good background knowledge of cancer genetics/biology is desirable
Excellent problem solving and project management skills is required whilst working independently on projects to meet tight deadlines
How to Apply
All applications must include a cover letter, resume including at least 2 referees and copies of relevant qualifications / academic transcripts and apply in the company website. This position will remain open until filled. As we will be reviewing applications as they are received, we encourage you to submit yours as soon as possible.
Job website: http://garvan.wd3.myworkdayjobs.com/en-US/garvan_institute/job/Sydney/Research-Officer_PRF5464-1
Contact name: Michelle Earle
Contact email: m.earle@garvan.org.au