Sr Bioinformatics Scientist @ Illumina

Position title: Sr Bioinformatics Scientist

Employer: Illumina

Closing date: 31 Jan 2022

Brief position description: Our team develops Next Generation Sequencing (NGS) secondary analysis solutions used by researchers and clinicians worldwide, providing sample-to-answer pipelines with high reliability, speed, and accuracy of results.

We are responsible for the industry-leading FPGA-accelerated DRAGEN platform, high-performance software, and integration of pipelines into in the ICA Cloud and BSSH platforms for automation, scalability, and data interpretation. The platform caters to a wide variety of applications, from rare and undiagnosed inherited diseases, population-scale genetics, precision medicine, cancer research, COVID-19 testing, metagenomics, single-cell analysis, etc.

We are looking for a highly driven and talented bioinformatics scientist to join our methods development team to work on various aspects of secondary analysis pipelines, large variant calling (SV, CNV), small variant calling (SNV) or RNA. The ideal candidate will be able to contribute both to the algorithm design based on bioinformatics/algorithm/statistics background, and to the software code base, based on proficient C/C++ programming skills.

Responsibilities:
• Algorithm development – Design, develop, and maintain highly accurate computational algorithms for large-scale analysis of novel types of genomic data
• Data analysis – Lead investigation and resolution of technical problems, applying best practice statistical/computational methods
• Pipeline development – design and develop pipelines in production-grade C/C++ software
• Collaboration -- Closely interact with product owners, systems engineers, testers, and FPGA design teams.
• Support -- provide technical assistance to escalated production issues.
• Leadership -- Provide technical leadership to an Agile team if required. Maintain awareness of industry trends and evaluate applicability of new software technologies to platform development efforts.

Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs.

Required Skills and Experience:
• PhD with 5+ years’ experience in academic or industrial settings in Bioinformatics, Computational Biology, Biostatistics or Computer Science, or equivalent experience
• Experience developing next generation sequencing data analysis methods for DNA and/or RNA sequence
• Extensive experience in an object-oriented programming language; C++ preferred
• Strong background in computer science algorithms relevant to bioinformatics
• Strong communication skills and ability to describe complex analyses to audiences with diverse backgrounds
• Ability to contribute independently and collaboratively, take ownership of assigned tasks, and excel in a fast-paced environment
• Experience with using version control systems such as Git

Desired Skills and Experience:
• Experience with scripting languages, including Python and bash
• Experience with multi-threading and memory management techniques.
• Knowledge and experience with probability and statistics and/or machine learning
• Knowledge and experience with cloud application development, in particular AWS
• Knowledge and experience with a wide range of bioinformatics tools
• Familiarity with professional software development practices (testing, CICD, debugging, source control, etc.)
• Demonstrated success in collaborating in a team environment and delivering high-quality software products using agile development methodologies

Job website: http://illumina.wd1.myworkdayjobs.com/illumina-careers/job/Australia---Remote/Sr-Bioinformatics-Scientist_29812-JOB

Contact name: David Lin

Contact email: david.lin@illumina.com