Senior Research Scientist/Bioinformatician @ Sydney

Position title: Senior Research Scientist/Bioinformatician

Employer: Blood, Stem Cell and Cancer Research Program, St Vincent's Hospital Centre for Applied Medical Research (Sydney)

Closing date: 27/02/20

Brief position description: We seek an experienced post-doctoral scientist/bioinformatician with proven next-gen sequencing (NGS) analysis experience to join the Blood, Stem Cell and Cancer Research Program of Professor David Ma in the St Vincent’s Centre for Applied Medical Research (AMR).

Our multifaceted program includes the study of haematopoietic stem cells with an emphasis on understanding molecular gene regulation and cellular alteration underpinning the formation of blood malignancy; the identification of novel drug targets and therapeutic approaches for acute leukaemia; and investigating age-related haematological mutations and their association with disease. The successful applicant would have demonstrated experience in the analysis of NGS data, with specific knowledge of bioinformatic/statistical techniques for the analysis of rare somatic mutations, with knowledge of population genetics/GWAS highly desirable. A track record in publications and experience in grant applications will be highly regarded.

The successful candidate will be expected to work in a multi-disciplinary team. The position is available for 12 months with the likelihood of renewal. Salary and conditions will be in accordance with qualification and experience.

The vacancy is only open to Australian citizens, New Zealand citizens who hold a valid New Zealand passport, Australian permanent residents and those non-residents deemed by the Department of Immigration and Citizenship to be eligible to work in Australia.

For further information contact Dr Tim Molloy (t.molloy@amr.org.au).

Job website: http://www.seek.com.au/job/40954286

Contact name: Tim Molloy

Contact email: t.molloy@amr.org.au

Postdoc Position - Bioinformatics @ Sydney

Position title: Postdoc Position - Bioinformatics

Employer: Centenary Institute

Closing date: 27/02/2020

Brief position description: We are seeking an innovative and enthusiastic bioinformatician to work with a team of researchers headed by Doctor Ulf Schmitz, in the areas of transcriptomics, RNA biology and cancer. Building on the recent discoveries we are currently investigating the roles of alternative splicing and microRNA-mediated gene regulation in diverse human and mouse cells and tissues. We are also expanding our study to define the interplay between aberrant epigenetic modifications that contribute to splicing abnormalities relevant to cancers. We are committed to support and mentor young investigators to become group leaders in the future.

Your main role will be to conduct bioinformatics analyses in collaboration with a team of wet-lab researchers for a fixed term while participating in the activities of Centenary.

We are looking for exceptional candidates with:
• A recent PhD (preferably within the last 1-2 years) or about to be awarded a PhD in the relevant areas of computational biology/ bioinformatics, however more experienced investigators will also be considered;
• Extensive experience in NGS data analysis, pipeline development and algorithm implementation/development;
• Solid research experience, including first author publications in top journals;
• Ability to write/contribute to journal articles, grants and keep meticulous notes;
• Strong interpersonal, written and oral communication skills with an ability to liaise with a diverse range of people
• A strong team focus; and
• A demonstrated commitment to Occupational Health and Safety.

Desirable:
• A strong background in statistics and/or application of statistics for data analysis;
• Familiar with blood cell development and related malignancies, or breast cancers;
• Experience with systems biology and/or systems medicine workflows
• A demonstrated ability to supervise junior staff and students.

Job website: http://www.seek.com.au/job/40901531?_ga=2.109677312.446191821.1580699994-502531155.1574214385&_gac=1.216190242.1580354302.EAIaIQobChMI--_jw66q5wIVFIWPCh1IAA06EAAYASAAEgLiz_D_BwE

Contact name: Ulf Schmitz

Contact email: u.schmitz@centenary.org.au

Research Fellow - Phylogenetics @ Sydney

Position title: Research Fellow - Phylogenetics

Employer: University of Technology Sydney

Closing date: Wednesday 4th March 2020

Brief position description: • Early career research role
• Full-time role for fixed term of 2 years
• Base Salary PLUS 17% superannuation

The UTS ithree institute is looking to appoint a Research Fellow to work on a project looking at real-time phylogenetics for food-borne outbreak surveillance. The project aims to introduce, for the first time, real-time evolutionary analysis of agricultural pathogens so that outbreaks affecting crops and the food supply can be managed precisely and rapidly. An expert team will implement a large-scale data analytics framework in user-friendly software that integrates Australian infectious disease genomics data with global data. Expected outcomes include new knowledge of statistical algorithms for evolutionary analysis, relevant to biological disciplines beyond infectious disease; and enhanced capacity for infectious disease analysis.

About the role
In this role, you will develop and publish real-time surveillance algorithms to detect and track food-borne outbreaks and analyse microbial data using bioinformatic tools. You will produce high quality publications, and deliver presentations at research seminars and international conferences. You will also mentor a team of students in carrying out related research projects and may have the opportunity to engage in tutorial development and delivery.

Working alongside experts in the field, this is an ideal opportunity for an early career researcher to contribute to collaborative and innovative research while developing and enhancing their own research profile.

The successful applicant will work part of their time at the Elizabeth Macarthur Agricultural Institute, the NSW Department of Primary Industries Centre of Excellence for Plant and Animal Health.

About you
You will have previous research experience in bioinformatics and microbial genomics and population genetics. You will have a strong writing ability demonstrated by a developing record of peer-reviewed journal publications.

You will also have:
• Skills in software development in R, Python, Java, C or C++
• Skills in Linux command-line, HPC and cloud computing
• A PhD degree in bioinformatics, statistics, mathematics, physics, computer science, engineering or a related quantitative field.

A demonstrated interest in further developing skills in phylogenetics and evolutionary biology as well as Bayesian statistics would be highly regarded.

More information and a position statement available on the UTS website.

Job website: http://bit.ly/2UqGkZS

Contact name: Mathieu Fourment

Contact email: Mathieu.Fourment@uts.edu.au

Research Associate - Phylogenetics @ Sydney

Position title: Research Associate - Phylogenetics

Employer: University of Technology Sydney

Closing date: Wednesday 4th March 2020

Brief position description: • Early career research role
• Full-time / part-time flexibility
• Base Salary PLUS 17% superannuation

About the role
In this role you will be tasked with developing and publishing novel theorems regarding statistical efficiency, producing high quality publications, and delivering presentations at research seminars and international conferences. You may also have the opportunity to engage in tutorial development and delivery.

Working alongside experts in the field, this is an ideal opportunity for an early career researcher to contribute to collaborative and innovative research while developing and enhancing their own research profile.

About you
You will have previous research experience in data science with solid skills in Bayesian statistics and computational statistics (Monte Carlo methodology, sequential Monte Carlo, Markov chain Monte Carlo). You will have a strong writing ability demonstrated by a developing track record of peer reviewed publications.

You will also have:
• Skills in programming languages such as R and python
• A PhD degree in statistics, mathematics, physics, computer science, engineering or a related quantitative field.

A demonstrated interest in further developing skills in HPC and cloud computing; and applying quantitative skills to biological problems related to the field of phylogenetics and evolutionary biology would be highly regarded.

More information and a position statement are available on the UTS website.

Job website: http://bit.ly/380J5oK

Contact name: Mathieu Fourment

Contact email: Mathieu.Fourment@uts.edu.au

Bioinformatician in Computational Functional Genomics @ New South Wales

Position title: Bioinformatician in Computational Functional Genomics

Employer: Children’s Medical Research Institute (CMRI)

Closing date: Friday 28th February 2020

Brief position description: We are seeking a qualified Bioinformatician / Data Scientist to join the Functional Genomics program. This role will involve supporting researchers from the CMRI and collaborating institutions in the analysis of multi-omic data of rare genetic diseases, disease modelling and single-cell analytics. The successful applicant will have opportunities to explore and interrogate a diverse range of data, including genomics, epi-genomics, transcriptomics, and clinically relevant sequence data. Additionally, the successful applicant will work alongside highly experienced research data scientists/bioinformaticians.

Children’s Medical Research Institute (CMRI) was Australia’s first dedicated paediatric research facility and is one of the nation’s most highly regarded independent medical research centres. Our research focuses on embryonic development, cancer, neuroscience and gene therapy and we have a strong international reputation based on our research outcomes. CMRI’s research programs are supported by state of the art facilities and committed research and support staff. Our achievements are made possible by a loyal network of community supporters, highly engaged donors and the very successful Jeans for Genes® fundraising campaign.

Job website: http://www.cmri.org.au/getattachment/About-Us/Job-Vacancies-and-Careers/Bioinformatician,-Computational-Functional-Genomics-(PV2005).pdf.aspx?lang=en-AU

Contact name: Patrick Tam

Contact email: ptam@cmri.org.au

Research Fellow - Klebsiella pneumoniae genomics and metabolic modelling @ Melbourne

Position title: Research Fellow - Klebsiella pneumoniae genomics and metabolic modelling

Employer: Monash University

Closing date: February 29 2020

Brief position description: We are recruiting a Research Fellow to work on an exciting new project exploring metabolic diversity in Klebsiella pneumoniae, a World Health Organization priority pathogen. The appointee will use a combination of comparative genomics and genome-scale metabolic modelling approaches to investigate how metabolic capabilities are distributed in the K. pneumoniae population.

K. pneumoniae is a ubiquitous bacterium that can inhabit a broad range of hosts and environmental niches. It is also extremely diverse with access to a gene-pool of more than 100,000 genes, at least a third of which are predicted to encode proteins with metabolic functions, indicating that metabolic capability varies substantially between strains. This is of particular interest because metabolic capacity is considered a key driver of niche preference and the ability to cause disease in different hosts or body sites.

This genomics-focused position is suitable for an individual with strong undergraduate and graduate training in a relevant area of biology (molecular biology, genetics, microbiology, biochemistry, evolutionary biology) as well as demonstrated skills and/or training in a quantitative discipline (statistics, computing, mathematics). The ideal candidate will have experience working with high-throughput genomic data from bacteria, with experience in using command-line programs, as well as writing and troubleshooting code in Python and/or similar programming languages. Previous experience in genome-scale metabolic modelling is helpful but not required.

The appointee will be supervised by Dr Kelly Wyres and Prof Kathryn Holt; will interact with research scientists, students, and administrative staff of Monash University; and collaborate closely with other members of the laboratory, the Department, and international collaborators at the University of California San Diego (USA) and Institut Pasteur (France).

12 month fixed-term appointment with possibility for extension.

Job website: http://careers.pageuppeople.com/513/cw/en/job/601348/research-fellow-klebsiella-pneumoniae-genomics-and-metabolic-modelling

Contact name: Kelly Wyres

Contact email: kelly.wyres@monash.edu

Bioinformatician in Computational Functional Genomics @ New South Wales

Employer: Children's Medical Research Institute

Closing date: 28/02/2020

Brief position description: We are seeking a qualified Bioinformatician / Data Scientist to join the Functional Genomics program. This role will involve supporting researchers from the CMRI and collaborating institutions in the analysis of multi-omic data of rare genetic diseases, disease modelling and single-cell analytics.

Job website: https://www.cmri.org.au/About-Us/Job-Vacancies-and-Careers

Contact name: Paulina Baranowski

Contact email: pbaranowski@cmri.org.au

 Biostatistician- ProCan @ New South Wales

Employer: Children's Medical Research Institute

Closing date: 21/02/2020

Brief position description: A Biostatistician position is available in the ProCan Cancer Data Science Group, led by Dr. Qing Zhong. ProCan (the ACRF International Centre for the Proteome of Human Cancer) is a world-first initiative developed and launched in September 2016 by Professors Phil Robinson and Roger Reddel, and established with a $10 million grant from the Australian Cancer Research Foundation (ACRF). Equipped with six SCIEX mass spectrometers and a super computer (800TB / 480 cores), ProCan processes tumour samples through a proteomic method, SWATH-MS, which allows fast mass spectrometric conversion of small amounts of tissue (biopsy level) into a single, permanent digital file representing the quantitative proteome of the sample.

Job website: https://www.cmri.org.au/About-Us/Job-Vacancies-and-Careers

Contact name: Paulina Baranowski

Contact email: pbaranowski@cmri.org.au

Clinical Bioinformatician @ Sydney

Position title: Clinical Bioinformatician

Employer: Neuroscience Research Australia

Closing date: 5PM Wednesday 5th February

Brief position description: This position will support the molecular genetics laboratory, Mackenzie's Mission and the CRE-NCD by assisting with clinical cloud-based bioinformatics requirements for the analysis of next generation sequencing (NGS) data, implementation and maintenance of bioinformatics pipelines around design, performance, validation and quality control. The clinically targeted NGS panels, exomes or genomes and bioinformatics pipelines require embedded bioinformatic expertise. NGS data analysis using computer programming and Unix-based servers is required. This is also largely a development role, so experience with front-end and back-end development and working with Amazon Web Services is desirable The successful candidate will be working closely with wet lab scientists, clinicians, pathologists, genomic analysts, and other bioinformaticians/software developers.

We are seeking an experienced and motivated development Bioinformatician interested in applying their skills in a clinical setting and able to work both independently and as part of a team. This is a full time position for two years.

Job website: https://www.seek.com.au/job/40675630?type=standard#searchRequestToken=6cf8acc7-3a6b-46a4-97e0-5ca79f2d6690

Contact name: Tony Roscioli

Contact email: Tony.Roscioli@health.nsw.gov.au

Postdoctoral Research Officer - DNA Repair and Recombination @ Melbourne

Employer: St Vincent's Institute of Medical Research

Closing date: 14 February 2020

Brief position description: Facility

St Vincent’s Institute (SVI) www.svi.edu.au is an internationally recognized independent research organization, based on the St Vincent’s Hospital Campus on the edge of Melbourne’s CBD. The Institute has a dedicated team of over 150 staff and students, who are committed to improving the health and life-expectancy of Australians. We focus on common diseases that represent major health issues for Australians today, including infertility, diabetes, bone diseases, cancer, cardiovascular disease, obesity and Alzheimer’s disease. With an exceptional pool of talented researchers and a growing number of state-of-the-art facilities, we are enthusiastic about the future.

Laboratory & Research Focus:

The DNA Repair and Recombination Laboratory is an established research group at SVI, focused on understanding the genetic control of DNA repair and recombination. Our vision is to translate basic knowledge of DNA repair pathways into treatments for infertility, bone marrow failure syndromes and cancer. Our team is a dynamic research environment with 13 members (senior scientists, postdocs, post-graduate students, RAs) who all share a passion for research and having fun along the way.

Position

We are seeking a self-motivated and passionate postdoctoral Researcher to join the DNA Repair and Recombination Laboratory team headed by Dr Wayne Crismani. This role will manage a project focused on genetics, meiotic crossover formation and leveraging the power of single cell sequencing in gametes. The incumbent will work primarily as a wet-lab scientist, however, they will work closely with research bioinformaticians and statisticians for all experimental stages from planning through to data analysis.

Our laboratory has made significant advances already on the project and a driven post doc will have ample opportunities for high quality publications in broad interest journals plus those with a focus in genetics and method development.
The successful appointee will have a PhD (or equivalent) focused on genetics and molecular biology. A strong understanding of Mendalian genetics and breeding strategies is essential.

The appointee will be highly organised, excellent at maintaining laboratory records and a clear communicator. Applicants whose first language is not English are welcome to provide supporting documentation such as IELTS or TOEFL scores.
Salary: commensurate with experience ranging from $85,000 to $91,911 per annum, plus 9.5% superannuation and generous $15,900 FBT exempt salary packaging.

Position Descriptions: https://www.svi.edu.au/careers_students/careers/current_vacancies

Further information: Dr Wayne Crismani wcrismani@svi.edu.au
To apply: All applications addressed to Dr Wayne Crismani should include the following:
- Current CV (2 page maximum); and
- Cover letter addressing the selection criteria (1 page maximum).

Job website: http://www.seek.com.au/job/40774713?

Contact name: Dr Wayne Crismani

Contact email: wcrismani@svi.edu.au