Senior Scientist - Next Generation Sequencing @ NSW

Position title: Senior Scientist - Next Generation Sequencing

Employer: Garvan Institute of Medical Research

Closing date: 12/12/2021

Brief position description: The Garvan Institute of Medical Research (Garvan/Institute) is one of Australia’s leading medical research institutes, with over 700 scientists, students and support staff. Its mission is to make significant contributions to medical research that will change the directions of science and medicine and have major impacts on human health. Garvan’s research encompasses bone biology, cancer, diabetes and metabolism, genomics and epigenetics, immunology, and neuroscience. These research activities are organised within four encompassing Research Themes: Cancer, Genomics & Epigenetics, Healthy Ageing, Immunity & Inflammation, and three major Centres: the Kinghorn Centre for Clinical Genomics, the Garvan-Weizmann Centre for Cellular Genomics, and the Centre for Population Genomics.

KCCG Sequencing Laboratory (KCCGSL) assists realising this mission by providing accredited molecular genetics and genomic sequencing services to medical researchers utilising state-of-the-art sequencing & bioinformatics technologies, supported by industry-leading laboratory automation and high performance computing infrastructure.

The Opportunity
The KCCGSL senior scientist (NGS) will lead the continuous improvement of the laboratory through process review, improvement identification, stakeholder engagement as well as project design, planning and implementation. We are seeking an experienced NGS scientist that is a creative and proactive problem solver with excellent communication and project management skills. The successful candidate is expected to take on a leadership role within the laboratory, utilising their experience and expertise across multiple functions to enable the laboratory to meet its strategic goals.

This is a 2 year fixed-term fulltime position with a base salary between $93,298 and $105,578 (depending on experience) plus 10% superannuation, salary packaging benefits and flexible working arrangements.

Culture
The more these values sound like you, and describe the people you want to work with, the more likely you will thrive as a Garvanite:
• Innovative - We are curious, deep thinkers who challenge established ideas and prevailing assumptions – unafraid to do things differently.
• Inspire Excellence - We have the very highest standards – relentlessly pursuing excellence through continuous improvement
• Be Collaborative - We seek out diversity of thought in pursuit of the best possible outcome – valuing insights from across Garvan and beyond
• Act with Integrity - We do the right thing – acting ethically and respectfully, communicating openly, valuing diversity and embracing all perspectives.
• Be Brave - We take calculated risks and pursue brave choices – doing the hard things every day, to achieve the extraordinary

Key Responsibilities
The position will be responsible for the following activities:
• Work closely with the Laboratory Manager, Principal Scientist, Head of Research & Development, Project Manager and other team members to ensure timely and effective prioritisation of sequencing projects.
• Lead continuous improvement projects in the lab including but not limited to development of new QC procedures, introduction of new equipment or methods and LIMS workflow management.
• Participate and co-ordinate investigations to troubleshoot existing methods and processes as required within the sequencing lab and work cross functionally with the bioinformatics team to achieve a resolution.
• Design and manage experiments, independently interpret and report results.
• Manage and co-ordinate technical enquiries including project scoping for internal and external researchers.
• Actively participate in the training and mentorship of junior staff.
• Other duties as delegated

Snap shot of benefits
• Generous salary packaging ($15,900 for general household expenses and $2,650 for meal/entertainment allowance on top of base salary)
• On going training and development
• Flexible work arrangements
• 18 weeks paid parental leave
• Additional day’s leave as Garvan Day
• Discounted Health Insurance
• Lifestyle discounts with our community partners

About You
The key skills and experience include:
• Minimum Bachelor’s degree in Molecular Biology, Biotechnology or Genetics
• 3+ years of experience in utilising Next Generation Sequencing (NGS) technologies. Familiarity with illumina technology will be highly regarded.
• 2+ years of leadership experience preferred
• Experience in the maintenance of quality management systems in a regulated (ISO) environment
• Demonstrated experience in the implementation of new workflow processes such as laboratory information management systems (LIMS), automated liquid handling procedures and new equipment
• Demonstrated experience in project management and coordinating a team
• Proven ability to independently troubleshoot and resolve complex issues
• Proven ability to handle a range of technical enquiries from diverse applications
• Ability to assess and organise resources, and to plan and progress work activities to strict deadlines.
• Excellent written and verbal literacy skills to prepare and present various reports

How to Apply
To apply for this position, please submit your application with a CV and cover letter as one document, stating why you are interested in this role. We are reviewing applications as they are received. If you think you’re the right person for this role, we’d love to hear how your capabilities, achievements and experience set you apart. Only applicants with full working rights in Australia are eligible to apply for this role.

Job website: https://garvan.wd3.myworkdayjobs.com/en-US/garvan_institute/job/Sydney/Senior-Applications-Scientist_PRF6084-1

Contact name: Talent Team

Contact email: talent@garvan.org.au

Computational Biologist / Bioinformatics Data Scientist @ QLD

Position title: Computational Biologist / Bioinformatics Data Scientist

Employer: James Cook University

Closing date: 02/12/21

Brief position description: We offer an exciting opportunity for a Computational Biologist / Bioinformatics Data Scientist (salary $68,350 - $113,201) to join our world-leading institution at James Cook University (JCU). A full time, fixed term appointment to 31 December 2024, this position is based at JCU Bebegu-Yumba campus in Townsville.

What you can accomplish in the Role:
James Cook University (JCU) is a world leader in specific areas of the molecular life sciences, and tropical/infectious diseases. Building on our recent discoveries, we are now seeking an innovative and enthusiastic early career researcher to work in the areas of bioinformatics software development, multi-omics data analysis, RNA biology and cancer. Collaborating with a strong group of professionals, you will have the opportunity to develop and conduct teaching and research activities in bioinformatics/computational biology in relation to basic molecular biology and in non-communicable diseases such as cancer.

What you will bring to the Role:
You will have recently completed, or about to be awarded, your PhD, on the relevant areas of bioinformatics, computational biology, software engineering, biostatistics or related disciplines and have experience in next generation sequencing data analysis (genomics, transcriptomics, epigenomics) and machine learning. You will demonstrate enthusiasm and capacity for teaching bioinformatics/computational biology and will contribute to research activities, including sourcing and applying for new funding, and will actively publish in internationally peer reviewed literature.

Why JCU:
JCU offers a culturally diverse working environment with opportunities for professional and personal growth as well as diverse career opportunities. JCU prides itself on being dedicated to teaching, learning and research that is not only of high quality, but also delivers practical benefits to the peoples and industries of the region.

We support our people through the provision of:
• generous superannuation scheme with 17% employer contributions
• ongoing professional and career development
• attractive options for salary packaging

How to Apply
Visit the Careers at JCU website - vacancy reference 17672

Job website: http://myhronline.jcu.edu.au/ords/hrprodords/WK8227$VDC1.Startup?P_VACANCY_REF_NO=17672

Contact name: Ulf Schmitz

Contact email: ulf.schmitz@jcu.edu.au

Technology Manager - Bioinformatics @ NSW

Position title: Technology Manager - Bioinformatics

Employer: Australian Proteome Analysis Facility - Macquarie University

Closing date: 10 November 2021

Brief position description: This role will lead the Bioinformatics team at the Australian Proteome Analysis Facility (APAF) at Macquarie University. Reporting to the APAF Manager you will contribute to the development and delivery of APAF's strategy, taking a lead role within the specialist stream of Bioinformatics. This role will involve working with clients and APAF staff to develop and implement optimal Bioinformatics solutions and analysis ensuring that they operate in a robust, accurate, cost effective and timely manner. You will manage and contribute expert advice for the day to day operations, projects, initiatives and resourcing for Bioinformatics, ensuring a highly professional and effective service is provided to clients, team members, users and stakeholders. And establish, implement, document and test informatics methods, tools and capabilities,and carry out validation and verification of tools and analyses to be used in NATA-accredited testing.

Job website: http://mq.wd3.myworkdayjobs.com/CareersatMQ/job/North-Ryde-Campus/Technology-Manager---Bioinformatics_R000003636-1

Contact name: Belinda Schiller

Contact email: belinda.schiller@mq.edu.au

Bioinformatician – Human Gut Microbiome Metabolism

Position title: Bioinformatician – Human Gut Microbiome Metabolism

Employer: Microba Life Sciences

Closing date: Open until filled

Brief position description: We are seeking an enthusiastic, talented and experienced computational biologist / bioinformatician of gut microbiome metabolism. Microba currently has a globally unique data set consisting of over 10,000 proprietary metagenomes, over 1 million high quality microbial genome sequences, and a large biobank of microbial isolates. In this role, you will build world-class bioinformatic applications and methodologies that describe the natural metabolic functions of these organisms and gut microbial ecology at scale. You will also assist in the interpretation of these results for internal and external stakeholders and in primary research activities to determine how interventional modulation of the microbiome can improve metabolic function of the gut microbiome. This is a senior role and would suit a biologist with applied bioinformatics skills or an experienced bioinformatician with a demonstrated track record in metabolism related research and tool development.

There are opportunities for publications, conference attendance and the production of white papers. This is a rare opportunity to apply your scientific expertise and skills to an innovative platform making a real impact on health and well being.

Key activities/duties

- Build annotation pipelines using Hidden Markov Models (HMMs) and other appropriate methods to functionally annotate gene sequences
- Determine through direct interrogation and/or validated imputation the core and secondary metabolic functions of genomes and species by reconstructing annotated pathways in-silico
- Quantification of community gene and pathway encoded potential in-vivo through development and application of appropriate bioinformatics and statistical methods
- Validate methods with targeted in-silico and in-vitro experiments.
- Interpret functional data for meaningful knowledge acquisition
- Assist internal teams for Research, Platform and Consumer products in communication of metabolic and functional information to clients
- Communicate results to external research and corporate clients as required
- Assist the Science Team to author in depth reports for corporate clients about functional outputs and experiment relevant functional signals

Job website: http://www.linkedin.com/jobs/view/2722248452/

Contact name: David Wood

Contact email: david.wood@microba.com

Bioinformatics postdoc @ VIC

Position title: Bioinformatics postdoc

Employer: St Vincent's Institute of Medical Research

Closing date: October 15th 2021

Brief position description: The DNA Repair and Recombination Laboratory is an established research group at SVI, focused on understanding the genetic control of DNA repair and recombination and the role that these processes play in inheritance and oncofertility. We are seeking a bioinformatician who loves what they do and who wants to work closely with wetlab researchers. You will be a key member of the team for all experimental stages from planning through to data analysis. You will be a self-motivated researcher with a PhD, first author publications and trained in bioinformatics and genomics, statistics, computation and reproducible analyses. The role will be a mixture of semi-autonomous research and providing support as required to the wetlab part of the team. You will have the opportunity to develop your own research projects by negotiation.

To address our biological questions, we use a number of tools that produce large datasets which includes: bulk high-throughput sequencing of genomic DNA, single-cell sequencing of genomic DNA, immunofluorescence microscopy, whole animal phenotyping from pedigrees, and other cell-based phenotypic datasets. The team is specifically interested in performing discovery research and identifying and characterising phenotypes which in turn improves our understanding of our biological interests.

Having a diverse workforce that represents the global and Australian community is very important to our team and we actively encourage applications from Aboriginal and Torres Strait Islanders, people with disabilities, from culturally and linguistically diverse backgrounds, LGBTQIA+ people, and all genders.

Please apply using the specific instructions on the Seek job ad.

Job website: http://www.seek.com.au/job/54189979?type=promoted#searchRequestToken=c6d6e91f-7ecf-4c20-b1c6-d0b371ae097e

Contact name: Wayne Crismani

Contact email: wcrismani@svi.edu.au

Research Assistant @ QLD

Position title: Research Assistant

Employer: The University of Queensland

Closing date: 8 October 2021

Brief position description: About This Opportunity
The Mowry Lab seeks an experienced Research Assistant with a background in Bioinformatics, Statistical Genetics, or a related field. The individual will be responsible for conducting sample and genetic variant quality control in genotyping and sequencing studies, developing and executing bioinformatics pipelines using high-performance computing clusters, and developing, deploying and managing research software for the proposed lab’s web portal.

Our Ideal Candidate
The ideal candidate will demonstrate computer programming experience and experience using Bioinformatics applications. They will also possess a Bachelors or Masters in Bioinformatics or related fields such as Computer Science, Mathematics or Statistics. Other desirable experience and skills include the following:

Experience in Machine/Deep learning
Experience in Statistical/population genetics
Experience in Next-generation sequence analysis
Experience in using Linux operating systems and cluster computing for analysing scientific data
Experience in programming using shell scripts, R, Python or JAVA
Experience in releasing opensource software (R or python packages for genomic data analysis)
Knowledge of Systems Biology

For application queries, please contact recruitment@uq.edu.au stating the job number in the subject line.
Please apply online via the job website.

Job website: http://search.careers.uq.edu.au/caw/en/job/516231/research-assistant

Contact name: Sathish Periyasamy

Contact email: s.periyasamy@uq.edu.au

Bioinformatics Research Officer: Large-scale cancer omics and methods development @ VIC

Position title: Bioinformatics Research Officer: Large-scale cancer omics and methods development

Employer: Walter and Eliza Hall Institute of Medical Research

Closing date: 18 October 2021

Brief position description: Job Description
An exciting new opportunity exists for a talented and motivated bioinformatics researcher to join our research team to develop bioinformatics methods and apply them to large-scale cancer genomics and other omics data from rare cancer, prostate cancer and melanoma.

About the position
The position will involve developing novel analytical methods for sequence data, including new technologies like long reads, and using these data to contribute to new insights into mutational processes in cancer.

The successful candidate(s) will join a dynamic team of computational scientists in a supportive and flexible working environment. They will be encouraged to develop new research directions that complement existing themes within the lab and have the opportunity to establish and contribute to collaborative research projects and to gain supervision experience.

Selection Criteria
The successful candidate(s) will have a PhD in Computer Science, Mathematics, Statistics, Bioinformatics or Computational Biology, strong computational and programming skills, experience developing new algorithms, some familiarity with machine learning, and a keen interest in cancer.

Job website: https://wehi.wd3.myworkdayjobs.com/en-US/WEHI/job/Parkville-Victoria-Australia/Bioinformatics-Research-Officer--Large-scale-cancer-omics-and-methods-development_JR0000229-1

Contact name: Tony Papenfuss

Contact email: papenfuss@wehi.edu.au

Scientific programmer @ ACT

Position title: Scientific programmer

Employer: The John Curtin School of Medical Research, Australian National University

Closing date: 30/09/2021

Brief position description: The Scientific Programmer will work on the improvements and extensions of scientific software tools in Eyras’ lab (https://github.com/comprna), and in particular, of RATTLE (https://github.com/comprna/RATTLE), for the reference-free reconstruction of transcriptomes from long-read sequencing, and SUPPA (https://github.com/comprna/SUPPA), for the study of differential splicing across multiple conditions. The position provides the opportunity to learn about the applications of these tools to study transcriptomes in the context of the projects being carried out in the lab. Further responsibilities involve helping in the compilation and running of the code in the National Computational Infrastructure (NCI), developing unit tests and tests with experimental datasets, regular reporting of the technical issues and progress back to the supervisor.

The University actively encourages applications from Aboriginal and Torres Strait Islander people. For more information on employment opportunities, contact our Indigenous Employment Consultant via: indigenous.employment@anu.edu.au

ANU values diversity and inclusion and is committed to providing equal employment opportunities to those of all backgrounds and identities. For more information about staff equity at ANU, visit https://services.anu.edu.au/human-resources/respect-inclusion

Job website: http://jobs.anu.edu.au/cw/en/job/542075/technical-officer-programmer

Contact name: Eduardo Eyras

Contact email: eduardo.eyras@anu.edu.au

Senior Research Scientist in Computational Biology @ ACT

Position title: Senior Research Scientist in Computational Biology

Employer: CSIRO

Closing date: 21st September 2021

Brief position description: We are seeking a motivated Senior Research Scientist – Computational Biology to join the Traits Program within CSIRO Agriculture and Food. The research this program is undertaking is increasingly involving complex machine learning and computational approaches to address biological problems at scale and deliver outcomes with industry impact.

As the successful candidate, you will contribute to this evolving digital transformation through engagement across a variety of project areas including host-microbe interactions and protein engineering. Using your skills and expertise in computational biology and fostering collaborations with internal and external stakeholders, you will address novel bioinformatic challenges and complex or ill-defined biological questions, and develop new research areas facilitated by data analytics, modelling and machine learning tools.

This role is offered on a full-time or part-time (minimum 0.8 FTE) basis.

Location: Canberra (Black Mountain) ACT
Salary: AU$115k – AU$135k (pro-rata for part-time) plus up to 15.4% superannuation
Tenure: Indefinite
Reference: 76770

For full details about the role, including a link to the position description, please view the advert on CSIRO's website.

Job website: http://jobs.csiro.au/job/Canberra%2C-ACT-Senior-Research-Scientist-in-Computational-Biology/786771200/

Contact name: Melania Figueroa

Contact email: melania.figueroa@csiro.au

Research Scientist – Human Gut Microbiome @ NSW

Position title: Research Scientist – Human Gut Microbiome

Employer: CSIRO

Closing date: 3rd October 2021

Brief position description: CSIRO Health and Biosecurity is seeking a motivated Research Scientist to join the Microbiomes for One Systems Health - Future Science Platform (FSP). The FSPs address new scientific challenges for Australia.

In this role, you will use your gut microbiology capabilities to define critical elements of the human gut microbiome and their metabolic products that are important for maintaining health or predicting disease states. This will include will applying current and emerging statistical, bioinformatic and modelling methods to the analysis of complex data. The research will contribute to the ultimate goal of constructing a working model of the ideal human gut microbiome which will lead to long-term health benefits for Australian and global communities.

The Microbiome FSP is developing new understanding of microbiome connectivity across the environment to human continuum and how system perturbations impact on microbiome functionality, diversity and systems health. A key objective is to capture greater benefit from microbiome interactions through more informative and predictive frameworks for functionality and by targeted interventions.

Location: Adelaide, SA or Sydney, NSW
Salary: AU$100k – AU$108k plus up to 15.4% superannuation
Tenure: Specified term of up to 3 years
Reference: 76412

Full details about this role, including a link to the position description, can be found on the advert on CSIRO's website

Job website: http://jobs.csiro.au/job/Sydney%2C-NSW-Research-Scientist-Human-Gut-Microbiome/785728500/

Contact name: Kim Fung

Contact email: kim.fung@csiro.au