Bioinformatician - Cancer Research @ VIC

Position title: Bioinformatician - Cancer Research

Employer: Peter MacCallum Cancer Centre

Closing date: 5 April 2023

Brief position description

This position will primarily support the analysis of single-cell RNA sequencing data at Peter Mac Research. Prior experience in single-cell data analysis is essential. This position will work and communicate closely with a team of cell biologists and bioinformaticians to address the analytical challenges posed by evolving genomic technologies.

Responsibilities
* Analyse single-cell RNA seq and other next generation sequencing data using best-practice methods and pipelines
Be exposed to cutting-edge research techniques in cancer therapeutics and contribute to solving related bioinformatics problems
* Develop pipelines and support data processing
* Apply computational and statistical methods to answer research questions
* Communicate work progress and results to researchers frequently

Qualifications
* A Master or higher degree in Mathematics/Statistics/Bioinformatics or equivalent, with outstanding academic results in final year subjects
* At least two years of experience in the analysis of next-generation sequencing data for human disease research
* At least one year of experience in single-cell RNA-seq data analysis
* Highly developed R and Python programming skills
* Experience working in a Unix environment and shell scripting
* Excellent verbal and written communication skills
* Strong interests in cancer research
* Proven ability to manage time effectively and be reliable and approachable

Job website: http://www.seek.com.au/job/66338853

Contact name: Jason Li

Contact email: jason.li@petermac.org

Bioinformatics Officer @ SA

Position title: Bioinformatics Officer

Employer: SA Genomics Centre (SAGC) / South Australian Health & Medical Research Institute (SAHMRI)

Closing date: Until filled

Brief position description: The South Australian Genomics Centre (SAGC) is a multi-institutional, national genomics and bioinformatics facility that is supported by Bioplatforms Australia (BPA) through the Australian Government’s National Collaborative Research Infrastructure Strategy (NCRIS). The SAGC has consolidated genomics and bioinformatics expertise in the state, with a group of ~10 genomics and bioinformatics staff working side-by-side to deliver innovative genomics and bioinformatics solutions across all areas of genomics research, including agriculture, healthcare and ecology

This is an exciting opportunity for a post-doctoral researcher or experienced MSc-level bioinformatician to join the SAGC bioinformatics team. To flourish in this role, you will need to be able to work across multiple different projects and to possess excellent organisational and time-management skills.

This role is primarily responsible for supporting SAGC users to appropriately design genomics-related projects and to analyse and interpret their data. Working collaboratively with researchers across different disciplines, you will have a varied and interesting workload across projects in different areas of genomics, leading bioinformatics analyses with varying levels of complexity. 

There are significant opportunities for professional growth and development through exposure to data sets from different genomics technologies including single cell and spatial transcriptomics. Staff are expected to enable research by leading the development of reproducible, standardised pipelines for genomics data analysis and, where necessary, develop new methods and pipelines. Your career development will be supported and you will be encouraged to publish your research and to collaborate on major funding applications to national and international funding bodies. 

You will also be supported to develop your bioinformatics capabilities; ensuring that the SAGC can remain at the forefront of genomics. It is expected that you will have interest in and develop your capabilities in at least one specialist area of bioinformatics.

About the Role
Key responsibilities include:
• Support researchers to design innovative but rigorous genomics projects and collaboratively support the bioinformatics aspects of these projects. 
• Develop and maintain reproducible bioinformatics pipelines and analyses approaches for routine analyses. 
• Where needed develop and implement new bioinformatics approaches, methods or data visualisation approaches. 
• Contribute to/or lead the drafting of reports and publications. 
• Contribute to/or lead the drafting of applications to major funding bodies.

About You
The successful candidate will possess the following key attributes:
• MSc, PhD, or equivalent experience, in either bioinformatics, computer science, physics, statistics or other relevant discipline
• Have a broad understanding of at least two of the following areas and a significant interest in developing a deep understanding in at least one:
o Transcriptomics: bulk RNAseq, scRNAseq, spatial transcriptomics, 
o Genomics: variant, haplotype and diversity analysis, genome assembly, metagenomics, epigenetics
o DevOps: version control: test driven development and continuous integration, containerisation using Docker/Singularity
o Systems biology: multi-omics data integration, network analysis
o Statistics: linear models, ANOVA, hypothesis testing
o Visualisation: data visualisation and User Interface/Experience design
o Workflow systems: Snakemake and/or Nextflow
o Other Omic's technology: metabolomics, proteomics
• Prior experience with at least one of the following scripting languages: bash, R, Python and Perl
• Minimum 2 years relevant work experience

Please see the website below for more information, position description and application process.

Job website: https://sahmri.org.au/careers-and-study/working-at-sahmri/vacancies/bioinformatics-officer-2

Contact name: Sen Wang

Contact email: Sen.Wang@sahmri.com

Postdoctoral position/Research Assistant @ NSW

Position title: Postdoctoral position/Research Assistant

Employer: Wong Lab, Victor Chang Cardiac Research Institute

Closing date: Until filled

Brief position description: Your next career opportunity
The Wong Lab is seeking a driven and motivated computational Postdoctoral Fellow to join the Regulatory Systems Laboratory at the Victor Chang Cardiac Research Institute. Our main goal is to understand gene regulatory control, in the context of evolution, development, in health and aging, using comparative methods, novel technologies and animal models. Our lab has capability in computational and experimental methods.

In this role you will have the opportunity to study the genetic and molecular mechanisms underpinning regulatory element function using high-throughput data and other impactful projects. You will receive support from a collaborative inter-disciplinary team of scientists in molecular biology, computer science, and genomics.

Does this sound like you?
​PhD in computational biology, genomics, computer science or a related discipline
Passion for biology in particular gene regulation / genome biology / epigenetics
Extensive experience with R/Python/HPC usage
Excellent biostatistics skills
Excellent written communication skills and the ability to communicate and critically interpret results

Job website: http://www.victorchang.edu.au/careers/jobs-available

Contact name: Emily Wong

Contact email: e.wong@victorchang.edu.au

Group Leader - Computational Biology @ VIC

Position title: GROUP LEADER – COMPUTATIONAL BIOLOGY

Employer: Peter MacCallum Cancer Centre

Closing date: 1 June 2023

Brief position description: We are recruiting up to two Group Leaders to increase the capacity and efficiency of our “discovery to translation” cancer research pipeline. We have a specific focus on building and expanding our Computational Biology Program that uses mathematics, statistics and computing to generate new discoveries in cancer. There are strong synergies between researchers in this program and the other research programs at Peter Mac that provide a breadth of collaborative opportunities for the new appointee. The Group Leader will develop and lead a team conducting internationally significant and innovative research to enhance our understanding of cancer development from fundamental biological principles of cancer to progression, evolution and translation into clinical practice.

The Group Leader is responsible for ensuring that their group’s financial and operational processes are sustainable and in accordance with regulatory, commercial and ethical obligations. They will be driven to achieve excellence in research outputs, mentorship and make a significant contribution to the local, national and international scientific communities.

Appointments will be considered at the level of new group leader (Level C) through to experienced Associate Professor (Level D).

Job website: http://careers.petermac.org/job/MELBOURNE-Group-Leader-VIC-3000/937192610/

Contact name: Alicia Oshlack

Contact email: Alicia.Oshlack@petermac.org

Research Fellow (Bioinformatician) @ VIC

Position title: Research Fellow (Bioinformatician) - Blood Cancer Biomarkers

Employer: Monash University

Closing date: Tuesday 21 March 2023, 11:55pm AEDT

Brief position description: We are seeking an outstanding candidate to join the Blood Cancer Biomarkers Laboratory as a post-doctoral Research Fellow (Bioinformatician). The successful candidate will lead projects in the field of circulating tumour DNA where they will be analysing whole genome and transcriptome sequencing data from patients with haematologic malignancy. Working closely with the Head of the Blood Cancer Biomarkers Laboratory, Dr Paul Yeh, the role will also involve close collaboration with senior bioinformaticians at Peter MacCallum Cancer Centre. The Research Fellow will develop their own research project to expand their own research program and profile, however, will also have an integral role in supporting members of the laboratory.

The appointee will have a doctoral qualification in the relevant discipline area or equivalent qualifications or research experience. Experience in bioinformatic analysis of next generation sequencing, specifically analysis of whole genome sequencing, whole transcriptome sequencing and whole exome sequencing, working with clinical samples including blood, tissue and fluid samples and translational research in cancer or haematology will see you successful in this role.

Diversity is one of our greatest strengths at Monash. We encourage applications from First Nations people, culturally and linguistically diverse people, people with disabilities, neurodiverse people, and people of all genders, sexualities, and age groups.

Job website: http://careers.pageuppeople.com/513/cw/en/job/648346/research-fellow-bioinformatician-blood-cancer-biomarkers

Contact name: Paul Yeh

Contact email: paul.yeh@monash.edu

Postdoc in In-silico glycomics @ Copenhagen

Position title: Postdoc in In-silico glycomics (Machine Learning/bioinformatics) at Department of Cellular and Molecular Medicine (ICMM)

Employer: University of Copenhagen

Closing date: 2/04/2023

Brief position description: We are looking for a highly motivated and dynamic scientist for a 2-year postdoctoral position to commence on 1 June 2023 or after agreement.

The position will be based in the Joshi Group at the Copenhagen Center for Glycomics (CCG) at the Department for Cellular and Molecular Medicine (ICMM) within the University of Copenhagen.

Information on the group can be found at: The Joshi Group web page (https://icmm.ku.dk/english/research-groups/joshi-group/) and https://smex-ctp.trendmicro.com:443/wis/clicktime/v1/query?url=https%3a%2f%2fglyco.me&umid=bfae75bb-278d-4071-9397-9c9e759538c0&auth=2af5473c4b03509246eb08bd803a6cf835f69953-20b8a5ea06b7a3745ff5c145c743f728cc4565d8

Our research:

The Joshi/In-silico glycomics Group uses data science to uncover the contributions from regulation of hundreds of glycosylation related genes to the overall glycosylation process that takes place in the endoplasmic reticulum and Golgi. We take advantage of both a massive amount of publicly available data, and unique genetically engineered cell lines and world leading wet-lab facilities for validation. We value our creative, open, and collaborative work environment, placing special emphasis on training and mentorship to help our colleagues reach their career goals. 

Your job:

Your tasks will include designing experimental strategies, identification and analysis of complex datasets using data science techniques, generation of validation data, and presentation of your research (including writing scientific manuscripts). Additional tasks could include contributing to grant applications, research-based supervision of MSc and PhD students, teaching undergraduate courses, and outreach communication activities. The successful candidate will play an integral role in establishing the lab and research environment.

Job website: http://employment.ku.dk/all-vacancies/?show=158678

Contact name: Hiren Joshi

Contact email: joshi@sund.ku.dk

Head of Bioinformatics @ VIC

Position title: Head of Bioinformatics

Employer: Burnet Institute

Closing date: 28/3/2023

Brief position description: Are you an established Bioinformatics expert seeking your next senior leadership opportunity? Would you like to play an integral role in driving meaningful and impactful health initiatives? Then this could be the role for you! 

We are now on the lookout for a Head of Bioinformatics to join our team at Burnet! You will play a key role in building bioinformatics capacity and capability to catalyse transformational research to achieve the Burnet 2030 purpose: to create and translate knowledge into better health, so no-one is left behind.

You will provide leadership across the organisation and will be responsible for building bioinformatics as a key research platform with the potential to establish a specific working group in the future. You will collaborate with existing working groups to provide high quality bioinformatics support and build technical capacity and best practice in the conduct of OMICS experiments and analysis of OMICs data. 

In this role, you will also:
•Identify and engage researchers with bioinformatics skills to lead a community of best practice 
•Provide high quality bioinformatics support, advice, and training to staff/students
•Conduct bioinformatics analysis for Burnet staff/students, and externally
•Support development of software packages for genomic, transcriptomic, proteomic and metabolomic, multi-omics data relevant to Burnet research
•Support development of best practice in bioinformatics coding, pipelines, workflows, and version control
•Collaborate with working groups to attract independent grant funding to build the bioinformatics platform 
•Make intellectual contributions in generating, analysing and interpreting research data
•Design and conduct bioinformatics workshops, drop in sessions, and/or tailored training of staff and students 
•Co-supervise and contribute to scientific mentoring of Honours/PhD/Masters students and staff

This is a full-time position, initially for a 7-year period with possibility of extension upon review.
This is truly a unique opportunity to shake up an industry, make a meaningful impact, and put your name on it. Don’t miss out! 

Role location 
Although we would prefer the incumbent be based in Melbourne, we are also accepting applicants based Australia wide to conduct the role remotely with once a month travel to our Melbourne office. Travel expenses will be provided by the institute as well as relocation expenses for candidates willing to relocate to Melbourne. 

Let’s talk about you

The following criteria are essential requirements:
•Experience in biological or medical research 
•Experience in general bioinformatics skills i.e. NGS data/genomics/transcriptomics
•Experience in single cell transcriptomics or metaproteomics or metabolomics or multi-OMICs bioinformatic analyses 
•Experience in writing code, proficiency in R, Python and/or other programming language for data analysis 
•Knowledge of biostatistics relevant to OMICs analyses
•Proven interpersonal and collaborative skills in achieving research outcomes
•Proven skills in communicating and teaching bioinformatics 
•Proven ability in maintaining accurate and detailed records of bioinformatic analyses, and data management

The following experience is also desirable: 
•Research experience that has resulted in publications, conference presentations or reports or other tangible outputs
•Proven ability to effectively prioritise tasks and develop timelines for completion of milestones to achieve project goals
•Experience in building bioinformatics capacity in a research setting
•Experience in high performance computing (HPC) systems administration 
•Demonstrated ability and potential for excellence and productivity in research
•Ability to prepare applications for funding National/International opportunities
•Track record in gaining independent funding
•Experience in pipeline development 

Salary: $131,399 - $163,576 (depending on experience) + super + salary packaging

Please click on the website link for full details.

Job website: https://aurecruitment.actionhrm.com/myrecruit/newApplicationWizard.htm?pc=_GtNMcIyemZrYZBTvKtG2Qxx

Contact name: Sean Perera

Contact email: sean.perera@burnet.edu.au

Bioinformatician, ACRF Genomics Facility @ SA

Position title: Bioinformatician, ACRF Genomics Facility

Employer: SA Health

Closing date: 11:55 pm Friday 17th March 2023

Brief position description: About the institution

The ACRF (Australian Cancer Research Foundation) Cancer Genomics Facility sits within SA Pathology and is part of the Centre for Cancer Biology (CCB), an alliance between SA Pathology and University of South Australia. The Facility develops and provides leading edge Genomics Services to researchers in the CCB and other organisations in South Australia and interstate, with a focus on innovation and translation of research to enable new diagnostic tests. The Facility also provides NATA-accredited services to SA Pathology, SA's public pathology provider, for both inheritable disease and cancer genetic testing. 

About the role
The primary objective of the Bioinformatician is to contribute to the delivery of high-throughput genetic testing technologies by implementing, developing and maintaining genome analysis solutions for research and diagnostic applications. The candidate will participate in research activities, including research publications and applications for funding, as appropriate.

Job website: http://www.seek.com.au/job/61376373?type=standout#sol=650921df61dcef6bf2cf6dda72de71ba2d46c6e7

Contact name: Rob King

Contact email: Rob.King@sa.gov.au

Research Officer/Post-doctoral Scientist - Computational Systems Biology @ NSW

Position title: Research Officer/Post-doctoral Scientist - Computational Systems Biology

Employer: Children's Medical Research Institute

Closing date: 22 March 2023

Brief position description: Position Summary
The Computational Systems Biology (CSB) lab at CMRI is welcoming applications for a Research Officer/Post-doctoral Scientist to conduct research in the broad area of computational systems biology of stem cells and organoid systems. Our research focuses on the acquisition of particular cell identity and cell fate decisions during cell differentiation, and to translate such knowledge for stem cell engineering and regenerative medicine. In collaboration with the Stem Cell Medicine lab at CMRI, the CSB lab has established experimental techniques including single-cell multi-omics and spatial transcriptomics, and mass spectrometry-based proteomics and phosphoproteomics to profile human and mouse embryonic/adult stem cells and various stem cell-derived organoids (e.g., eye organoids, brain organoids, and heart organoids). This appointment is at CMRI and will be affiliated with the Faculty of Medicine and Health at The University of Sydney. The appointee is expected to lead their own projects, contribute to internal or external collaborations, and when possible guide student research. The ability to work as part of a team is essential.

Position Compensation
Duration: Initially 2-year fixed term with potential for an 1-year extension (full time).
The candidate will be compensated with a competitive remuneration package in accordance with qualifications and experience. Additional benefits include the provision of a Public Benevolent Institution salary packaging scheme and participation in an employer-contributed superannuation fund.

Essential Characteristics
The appointee will be an ambitious post-doctoral scientist with a bold and creative approach to research. They will be capable of independent thought and project design, and will be able to work in a collaborative team setting. Exceptional candidates will be eligible for an internal CMRI post-doctoral fellowship, and the possibilities provided by this unique funding opportunity. The following characteristics and research experience are essential to this position.

• A PhD in computational biology, bioinformatics, applied statistics, computer science, systems biology and molecular biology or another closely related scientific discipline. Candidates in the final stages of PhD submission are welcome to apply.
• High proficiency with at least one programming language (e.g., R, Python).
• Demonstrated experience with data analytics in omics data analysis.
• Proven ability and commitment to produce high quality work, including track record of scientific publication.
• Proven research ability, and evidence of self-motivation and research potential.
• Proven excellence in written and oral communications, interacting with a variety of researchers and stakeholders.

Desirable Characteristics
• Knowledge of stem cells and molecular cell biology.
• Experience with deep learning.

Computational Systems Biology Lab
The CSB lab (https://pyanglab.github.io/) combines computational (‘dry’) and experimental (‘wet’) expertise to study cell identity and cell fate decisions of stem cells and organoids systems. The lab resides in CMRI, Westmead, while also holding office space both at the School of Mathematics and Statistics, and the Charles Perkins Centre, The University of Sydney. The CSB lab collaborates closely with other lab at CMRI (e.g., Stem Cell Medicine, Embryology) and is part of the Sydney Precision Bioinformatics Alliance and Sydney Precision Data Science Centre, The University of Sydney. The appointee will have ample opportunity to collaborate with bioinformaticians, statisticians, computational and systems biologists, and stem cells and developmental biologists within CMRI and from The University of Sydney.
Current focus of the CSB lab is on using computational approaches and bulk and single-cell multi-omics data to characterise cell identity and predict cell fate decisions for stem cell differentiation and organoid generation. The lab is currently supported by an NHMRC Investigator grant and two MRFF Stem Cell Therapies Mission grants. Most significant publications of the lab in the last five years appears in Cell Press and Nature Portfolio (http://pyanglab.github.io/publications.html) For more information please visit https://pyanglab.github.io/.

Application
Applications should include a cover letter (citing PV2250), curriculum vitae and contact details (phone/email) of three professional referees and be forwarded to recruitment@cmri.org.au.

Closing date for applications is (22 March 2023).

Please direct enquiries regarding the position to Associate Professor Pengyi Yang, NHMRC Investigator, pengyi.yang@sydney.edu.au.

Job website: https://www.seek.com.au/job/61377482

Contact name: Pengyi Yang

Contact email: pengyi.yang@sydney.edu.au

Research Fellow in Human Epigenetics (Bioinformatics) @ VIC

Position title: Research Fellow in Human Epigenetics (Bioinformatics)

Employer: Monash University

Closing date: 22 Feb 2023

Brief position description: Job No.: 646402

We are seeking someone with a doctoral qualification in the relevant discipline area or equivalent qualifications or research experience in Bioinformatics, Computer Science, Biological Sciences, Mathematics, Biostatistics or related fields. This position will require the appointee to have a track record and demonstrated experience in handling large epigenomic datasets that include but are not limited to DNA methylation sequencing.

Location: The Alfred Centre

Employment Type: Full-time

Duration: 2-year fixed-term appointment

Job website: http://www.seek.com.au/job/59851791

Contact name: Sam El-Osta

Contact email: sam.el-osta@monash.edu