Bioinformatics postdoctoral researcher: Large-scale cancer omics analyses and methods development @ VIC

Position title: Bioinformatics postdoctoral researcher: Large-scale cancer omics analyses and methods development

Employer: WEHI

Closing date: 30 June 2022

Brief position description: An exciting opportunity exists for a talented and motivated researcher to join our research team to apply and develop statistical bioinformatics methods for use with large cancer genomics and other omics datasets at Australia’s pre-eminent biomedical research institute. The position will involve applying and developing novel analytical methods for normalizing and integrating large cancer genomics and other omics datasets and using the results in collaboration with cancer researchers to contribute new insights into cancer. In the first instance the appointee will work with Profs Terry Speed and Tony Papenfuss and Dr Ramyar Molania on expanding the analyses presented in the publication "Removing unwanted variation from large-scale cancer RNA sequencing data" (Nature Biotechnology, to appear) to specific datasets of interest to WEHI cancer researchers. It is hoped that this line of research can then be continued and further developed to the point where we will have normalized and integrated essentially all major datasets of a given type on particular cancers of interest to researchers from WEHI (e.g. bulk RNA-seq breast cancer) and elsewhere in the Parkville Precinct. Collaborative research with these researchers through interrogating the integrated datasets should follow. Extensions to newer technologies such as single cell RNA-seq and multi-omic datasets, and spatial studies should naturally follow. A major goal here is the development of “big data resources and expertise” so that both wet and dry lab WEHI researchers can benefit from this initiative.

Job website: https://wehi.wd3.myworkdayjobs.com/en-US/WEHI/details/Bioinformatics-Research-Officer_JR929-1

Contact name: Terry Speed

Contact email: terry@wehi.edu.au

Post-Doctoral Researcher in Bioinformatics and Immune Oncogenomics @ VIC

Position title: Post-Doctoral Researcher in Bioinformatics and Immune Oncogenomics

Employer: Peter MacCallum Cancer Centre

Closing date: 28/06/2022

Brief position description: An excellent opportunity exists for an enthusiastic, motivated and skilled postdoctoral researcher to join the Goode and Parish Labs within the Computational Biology and Cancer Immunology Programs respectively. An exciting new collaborative research direction is currently being pioneered between the Goode and Parish Labs to design and apply analytical approaches to data from emerging high-throughput sequencing, single cell sequencing and spatial immune profiling technologies to investigate the role of the immune system in cancer. The advertised position will involve collaboration with both industry, and laboratory scientists conducting cutting-edge research in immune oncology. The successful applicant will be based within the Goode and Parish Labs at Peter Mac. Suitable candidates will possess a PhD and must have research experience and a strong track record in a relevant quantitative field, such as bioinformatics, physics, statistics, computer science or mathematics. They must also have advanced skills in a scripting programming language (such as R or Python), analysis of biological data, and development of novel algorithms or statistical analysis approaches. The successful candidate will be self-driven, possess a love of learning and have a friendly and enthusiastic disposition. Previous research experience in transcriptomics, single-cell data or spatial analysis would be an advantage. The position is initially for a fixed period of 12 months with potential for extension. Remuneration will be commensurate with qualifications and experience

Job website: https://petermac.mercury.com.au/ViewPosition.aspx?id=Jj9AgdVJ6E4=&jbc=ere

Contact name: David Goode

Contact email: david.goode@petermac.org

Senior Scientist, Translational Bioinformatics (Statistical Genetics) @ VIC

Position title: Senior Scientist, Translational Bioinformatics (Statistical Genetics)

Employer: CSL Innovation

Closing date: 19 June 2022

Brief position description: CSL has an exciting opportunity for a Senior Scientist, Translational Bioinformatics (Statistical Genetics) to join our team. In this newly created position, you will provide scientific and technical expertise to help answer biomedical research questions at the pre-clinical and clinical stage of drug development using advanced bioinformatics and human genetics methods. You will expand CSL’s R&D capability in Translational Bioinformatics (with a focus on Statistical Genetics) in order to derive biological insights from large-scale genetic/genomic data available in public and commercial databases, as well as in-house high-throughput sequencing and other ‘omic experiments.

You will work closely with scientists within the Data Science Group, the Translational Science Group and other Research and Clinical Development groups to set project objectives and to determine and implement data generation, data analytics, and bioinformatics platform development strategies. You will also work alongside CSL’s external collaborators including spending time in their research laboratories as required to enable alignment of objectives and bioinformatics strategies.

Job website: http://www.linkedin.com/jobs/view/3100799934

Contact name: Gad Abraham

Contact email: gad.abraham@csl.com.au

Post-Doctoral Bioinformatics Research Scientist @ VIC

Position title: Post-Doctoral Bioinformatics Research Scientist

Employer: University of Melbourne

Closing date: 24 Jun 2022

Brief position description: A post-doctoral bioinformatics scientist is required for the SUPER-NEXT study involving development of a novel diagnostic method involving whole-genome analysis of cancers of unknown primary.

SUPER-NEXT aims to evaluate complete genome sequencing and the use of liquid biopsies in a group of diagnostically challenging cancers, collectively known as cancers of unknown primary (CUP). SUPER-NEXT is recruiting CUP patients from more than 12 sites around Australia for centralised biobanking and genomic testing at the University of Melbourne Centre for Cancer Research (UMCCR) and the Peter MacCallum Cancer Centre, both located at the Victorian Comprehensive Cancer Centre. The SUPER-NEXT study is funded as part of the Medical Research Future Fund Genomics Health Future Mission.

The incumbent will undertake a project leveraging the resources of the SUPER-NEXT study that is focussed on developing a diagnostic method from cell free DNA in patient blood samples. The method will use whole genome sequencing for mutation signature detection and ctDNA fragment analysis. The project will be highly translational with the goal to develop a diagnostic tool ready for deployment in CUP in the short to medium term. The candidate will require prior experience with Linux-based high-performance computing environments, as well as experience with scripting languages such as R, Python, and Shell-script. A strong background in mathematics or statistics is also highly desirable.

Job website: https://jobs.unimelb.edu.au/caw/en/job/908903?lApplicationSubSourceID=

Contact name: Richard Tothill

Contact email: rtothill@unimelb.edu.au

Lead Computational Biologist @ VIC

Position title: Lead Computational Biologist

Employer: Peter MacCallum Cancer Centre

Closing date: 24/06/2022

Brief position description: The Cancer Genomics Translational Research Centre requires a highly experienced research scientist to take on the role of Lead Computational Biologist, with expertise in cancer genomics, bioinformatic methods, clinical informatics and statistics. In this exciting new role, the lead will be responsible for the co-ordination and execution of multiple translational research projects, including involvement in building and supervising of a team of staff. Key duties and responsibilities include (but are not limited to): - In conjunction with the Head of the Cancer Genomics TRC and other TRCs, the lead scientist will design, conduct and report on defined academic and commercial translational research projects. - Establish, train and mentor a team with capabilities across a range of different computational methods. - Work with other TRC members to establish an efficient data analysis workflow and data management structure. - In collaboration with other researchers, core faculties, the research computing facility and the clinical bioinformatics team, the lead scientist will research and develop innovative computational methods for use by the TRC, focusing on developing tools for clinical translation and potential commercial application.

Job website: http://petermac.mercury.com.au/ViewPosition.aspx?id=Cayf75659Rs=&jbc=ere

Contact name: Stephen Wong

Contact email: stephen.wong@petermac.org

Prostate Cancer Precision Medicine PhD Scholarship @ SA

Position title: Prostate Cancer Precision Medicine PhD Scholarship

Employer: Flinders University

Closing date: 30/06/2022

Brief position description: The Prostate Cancer Precision Medicine Scholarship is an exciting new research opportunity for a PhD student within the Flinders Health and Medical Research Institute at Flinders University. Our group has access to individual-patient data (demographic, clinical, laboratory and tumour data) from thousands of patients with advanced prostate cancer. The broad aim of the project is to use sophisticated data analytic methods (e.g. machine learning) to interrogate this unique dataset and, from there, develop tools and guidelines that enable more precise and effective patient treatment. This project represents an exciting and emerging field of research that uses “big data” to improve health outcomes. The successful candidate will be supervised by an outstanding multidisciplinary team comprising experts in clinical epidemiology, biostatistics and data analytics (Dr Ashley Hopkins, Professor Michael Sorich), prostate cancer biology (Associate Professor Luke Selth) and prostate cancer medical oncology and pharmacology (Dr Ganessan Kichenadasse).

Job website: http://www.flinders.edu.au/scholarships/prostate-cancer-precision-medicine-phd-scholarship

Contact name: Luke Selth

Contact email: luke.selth@flinders.edu.au

Bioinformatician @ VIC

Position title: Bioinformatician

Employer: Peter MacCallum Cancer Centre

Closing date: 15 June 2022

Brief position description: The primary responsibility of this role is to support the bioinformatics analysis of cancer research projects in the Bioinformatics Core Facility, and will work closely with Professor Ben Hogan and Dr Lizzie Mason in the Program for Organogenesis and Cancer, and other researchers at the Peter MacCallum Cancer Centre.

The Bioinformatics Core Facility aims to provide all levels of bioinformatics support to research laboratories within Peter Mac. The team of bioinformaticians and postdoctoral scientists at the core work alongside laboratory and clinical researchers and contribute to their experimental design, grant applications and the analysis and publication of genomic and transcriptomic data. The core also develops and maintains software infrastructure required for bioinformatics processing, including pipelines and cloud provision systems.

The successful candidate will have an Honour’s or Master’s degree in Bioinformatics, Computational Biology, Systems Biology, Computer Science, or equivalent. The candidate will have strong computational skills and experience applying them in the analysis of genomic data.

Job website: http://petermac.mercury.com.au/ViewPosition.aspx?id=Vm6Z7pbJhWk=&jbc=ere

Contact name: Richard Lupat

Contact email: richard.lupat@petermac.org

Bioinformatics Research Assistant @ VIC

Position title: Bioinformatics Research Assistant

Employer: Peter MacCallum Cancer Centre (Bioinformatics Core Facility)

Closing date: 15 June 2022

Brief position description: Outstanding candidates are encouraged to apply for positions now open at Peter MacCallum Cancer Centre – a place where our normal days are extraordinary; as are the people we care for. Peter Mac is one of a handful of integrated cancer research, education and treatment centres in the world. Each day our team strives to provide the very best in cancer care, even better treatments and potential cancer cures for all people affected by cancer. Globally, we are facing one of the most pivotal times in the pursuit of cancer cures, and Peter Mac stands at its forefront. Together, we aim to lead a new era of cancer prevention, care and discovery, supported by state-of-the-art facilities at our new home within the Victorian Comprehensive Cancer Centre building.

Your role in our future.

The primary responsibility of this role is to support the bioinformatics analysis of cancer research projects in the Bioinformatics Core Facility, and will work closely with Professor Ben Hogan and Dr Lizzie Mason in the Program for Organogenesis and Cancer, and other researchers at the Peter MacCallum Cancer Centre.

The Bioinformatics Core Facility aims to provide all levels of bioinformatics support to research laboratories within Peter Mac. The team of bioinformaticians and postdoctoral scientists at the core work alongside laboratory and clinical researchers and contribute to their experimental design, grant applications and the analysis and publication of genomic and transcriptomic data. The core also develops and maintains software infrastructure required for bioinformatics processing, including pipelines and cloud provision systems.

The successful candidate will have an Honour’s or Master’s degree in Bioinformatics, Computational Biology, Systems Biology, Computer Science, or equivalent. The candidate will have strong computational skills and experience applying them in the analysis of genomic data.

For further information about this opportunity, please review the position description or contact us for a confidential discussion.

Peter Mac requires its staff to be fully vaccinated against COVID-19. Please contact us if you would like to discuss this requirement.

Peter Mac offers its employees the following benefits:
Salary Packaging
Employee Assistance Program
Central City Location
Training and Development Program

Job website: https://petermac.mercury.com.au/ViewPosition.aspx?id=Vm6Z7pbJhWk=&jbc=ere

Contact name: Elizabeth Mason

Contact email: Elizabeth.Mason@petermac.org

Research Computing Engineer @ VIC

Position title: Research Computing Engineer

Employer: WEHI

Closing date: June 4, 2022

Brief position description: To support its world-class research, WEHI has made significant investments in developing a state-of-the-art computing environment, spanning traditional on-premise HPC and cloud, and the expertise to harness these resources.
The role is part of the Research Computing Platform team and will work closely with WEHI’s researchers and ITS team. It will involve development and optimisation of data analytic pipelines and tools, data management and data movement tools, database development, collaborative planning of hardware and software infrastructure, the development of policy and procedures, and researcher training.

The successful candidate will have excellent computing knowledge and skills, a capability to learn and acquire new skills, strong communication and interpersonal skills, good understanding of computational research and the needs of researchers, and strong software engineering experience. The role will be required to build and maintain strong collaborative relationships with all stakeholders.

Terms of appointment
This position is available for two years in a full time capacity, in the first instance. Salary is Professional Services Employee Level 7 ($92,193 - $99,800). Up to 17% superannuation and very attractive salary packaging options are available.

See the website for selection criteria.

Job website: https://wehi.wd3.myworkdayjobs.com/en-US/WEHI/details/Research-Computing-Engineer_JR879-1

Contact name: Julie Iskander

Contact email: iskander.j@wehi.edu.au

Bioinformatics Research Assistant @ VIC

Position title: Bioinformatics Research Assistant

Employer: Walter and Eliza Hall Institute of Medical Research

Closing date: 10/6/2022

Brief position description: There is an exciting opportunity for a talented and motivated researcher with an interest in genomics and gene regulation to join the laboratory of Prof Doug Hilton in the Blood Cells and Blood Cancer Division at the Walter and Eliza Hall Institute.
The Hilton lab aims to understand the cells of the blood system and how they communicate with one another.

Our multidisciplinary approach combines genomics, cell biology, imaging, molecular biology, evolutionary biology, bioinformatics and computational biology to understand how the different types of blood cell develop from their individual lineages.

This position will focus on analysis of genomic data, including RNA-Seq, ATAC-Seq, ChIP-Seq and single cell transcriptomics to help understand the role of candidate genes in blood cell production and the evolution of our haematopoietic system. Additionally there will be opportunities for image analysis and for maintenance and updating of visualisations for our data portal www.haemosphere.org

Job website: http://wehi.wd3.myworkdayjobs.com/WEHI/job/Parkville-Victoria-Australia/Bioinformatics-Research-Assistant--Hilton-Lab-_JR844

Contact name: Carolyn de Graaf

Contact email: degraaf@wehi.edu.au